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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using MBS7605613 (VCAM-1 Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)

Rabbit VCAM-1 Polyclonal Antibody | anti-VCAM-1 antibody

VCAM-1 Rabbit Polyclonal

Gene Names
Vcam1; VCAM1B
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
VCAM-1; Polyclonal Antibody; VCAM-1 Rabbit Polyclonal; anti-VCAM-1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
739
Applicable Applications for anti-VCAM-1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
Vascular cell adhesion molecule 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using MBS7605613 (VCAM-1 Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using MBS7605613 (VCAM-1 Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS7605613 (VCAM-1 antibody) at dilution of 1:1000)

Western Blot (WB) (HeLa cells were subjected to SDS PAGE followed by western blot with MBS7605613 (VCAM-1 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
81,246 Da
NCBI Official Full Name
vascular cell adhesion protein 1
NCBI Official Synonym Full Names
vascular cell adhesion molecule 1
NCBI Official Symbol
Vcam1
NCBI Official Synonym Symbols
VCAM1B
NCBI Protein Information
vascular cell adhesion protein 1
UniProt Protein Name
Vascular cell adhesion protein 1
UniProt Gene Name
Vcam1
UniProt Synonym Gene Names
Vcam-1; V-CAM 1; VCAM-1
UniProt Entry Name
VCAM1_RAT

NCBI Description

binds integrin very late antigen (VLA4); plays a role in cell adhesion [RGD, Feb 2006]

Uniprot Description

VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral

Cellular Component: apical part of cell; cell surface; early endosome; endoplasmic reticulum; external side of plasma membrane; extracellular space; filopodium; Golgi apparatus; integral to membrane; microvillus; podosome; sarcolemma

Molecular Function: amine oxidase activity; cell adhesion molecule binding; integrin binding

Biological Process: acute inflammatory response; aging; amine metabolic process; cell adhesion; cell-cell adhesion; cell-matrix adhesion; chronic inflammatory response; heart development; heterophilic cell adhesion; leukocyte adhesion; leukocyte tethering or rolling; membrane to membrane docking; positive regulation of T cell proliferation; response to ethanol; response to hypoxia; response to ionizing radiation; response to lipopolysaccharide; response to nicotine; response to nutrient; response to zinc ion; viral reproduction

Research Articles on VCAM-1

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Product Notes

The VCAM-1 vcam1 (Catalog #AAA7605613) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VCAM-1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's VCAM-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the VCAM-1 vcam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VCAM-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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