Immunohistochemistry (IHC)
(Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human VAMP2 / VAMP-2 Polyclonal Antibody | anti-VAMP2 / VAMP-2 antibody
Anti-VAMP2 / VAMP-2 Antibody (aa1-66) IHC-plus
Immunohistochemistry (IHC)
(Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Anti-VAMP2 antibody used in Western blot at 1:90000 dilution to detect 100ng of 19kDa recombinant VAMP2 protein antigen.)
Western Blot (WB)
(Anti-VAMP2 antibody used in Western blot at 1:90000 dilution to detect 100ng of 19kDa recombinant VAMP2 protein antigen.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]
Uniprot Description
VAMP2: a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin.
Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: cell junction; clathrin-coated vesicle; cytoplasmic vesicle; cytosol; integral to plasma membrane; intracellular membrane-bound organelle; membrane; neuron projection; perinuclear region of cytoplasm; plasma membrane; secretory granule; secretory granule membrane; SNARE complex; synapse; synaptic vesicle; synaptic vesicle membrane; terminal button; trans-Golgi network; vesicle; voltage-gated potassium channel complex; zymogen granule membrane
Molecular Function: calcium-dependent protein binding; calmodulin binding; identical protein binding; myosin binding; phospholipid binding; protein binding; protein C-terminus binding; protein complex binding; protein self-association; SNAP receptor activity; SNARE binding; syntaxin binding; syntaxin-1 binding
Biological Process: calcium ion-dependent exocytosis; cellular protein metabolic process; cellular response to insulin stimulus; energy reserve metabolic process; eosinophil degranulation; exocytosis; glutamate secretion; Golgi to plasma membrane protein transport; natural killer cell degranulation; neurotransmitter secretion; neutrophil degranulation; post-Golgi vesicle-mediated transport; protein complex assembly; protein transport; regulation of exocytosis; regulation of insulin secretion; response to glucose stimulus; synaptic transmission; synaptic vesicle exocytosis; vesicle fusion; vesicle-mediated transport
Research Articles on VAMP2 / VAMP-2
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Product Notes
The VAMP2 / VAMP-2 vamp2 (Catalog #AAA249641) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-VAMP2 / VAMP-2 Antibody (aa1-66) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VAMP2 / VAMP-2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (5 ug/ml). Researchers should empirically determine the suitability of the VAMP2 / VAMP-2 vamp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VAMP2 / VAMP-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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