Testing Data
Rabbit USP37 Polyclonal Antibody | anti-USP37 antibody
USP37 Antibody
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
USP37; Polyclonal Antibody; USP37 Antibody; anti-USP37 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
1789
Applicable Applications for anti-USP37 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
IHC: 1:100-1:500
WB: 1:500-1:1,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-USP37 antibody
Rabbit polyclonal USP37 (1) antibody was raised against a recombinate human USP37 protein 2-217aa (BC050461).
Product Categories/Family for anti-USP37 antibody
References
(1) Huang, X., Summers, M.K., Pham, V. et al. Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Mol. Cell 42 (4), 511-523 (2011).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
99,752 Da
NCBI Official Full Name
Homo sapiens ubiquitin specific peptidase 37, mRNA
NCBI Official Synonym Full Names
ubiquitin specific peptidase 37
NCBI Official Symbol
USP37
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 37
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 37
Protein Family
UniProt Gene Name
USP37
UniProt Synonym Gene Names
KIAA1594
Uniprot Description
Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).
Research Articles on USP37
Similar Products
Product Notes
The USP37 usp37 (Catalog #AAA8505761) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP37 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's USP37 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:500-1:1,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the USP37 usp37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP37, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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