Rabbit anti-Mouse Urea Transporter A1 Polyclonal Antibody | anti-SLC14A2 antibody
Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2)
Gene Names
SLC14A2; UT2; UTA; UTR; HUT2; UT-A2; hUT-A6
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry
Purity
Affinity by Purified Chromatography
Synonyms
Urea Transporter A1; Polyclonal Antibody; Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter); member 2; Slc14a2T; Solute carrier family 14 member 2; Urea transporter; kidney; Urea transporter 2; UrT1-C; UrT1-D; Ut2); Anti -Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter); anti-SLC14A2 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat UT-A1 at ~97kD and 127 kD. Species Crossreactivity: mouse.
Purity/Purification
Affinity by Purified Chromatography
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SLC14A2 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
Suitable for use in Western Blot and Immunocytochemistry.
Dilution:
Western Blot: 1:1000. 1ug/ml detected UT-A1 in 20 ug of rat kidney tissue lysate by colorimetric immunoblot analysis using IgG goat x rabbit (HRP) as the secondary antibody. Optimal diluitons to be determined by the researcher.
Dilution:
Western Blot: 1:1000. 1ug/ml detected UT-A1 in 20 ug of rat kidney tissue lysate by colorimetric immunoblot analysis using IgG goat x rabbit (HRP) as the secondary antibody. Optimal diluitons to be determined by the researcher.
Immunogen
Synthetic peptide corresponding to aa911-929 of the C-terminal tail of rat UT-A1 (NP_062220).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-SLC14A2 antibody
UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates transepithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promotor and expressed in the thin descending limb of Henle, viz. UT-A2).
Product Categories/Family for anti-SLC14A2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
urea transporter 2
NCBI Official Synonym Full Names
solute carrier family 14 (urea transporter), member 2
NCBI Official Symbol
SLC14A2
NCBI Official Synonym Symbols
UT2; UTA; UTR; HUT2; UT-A2; hUT-A6
NCBI Protein Information
urea transporter 2; urea transporter-2; urea transporter, kidney; solute carrier family 14 member 2
UniProt Protein Name
Urea transporter 2
Protein Family
UniProt Gene Name
SLC14A2
UniProt Synonym Gene Names
HUT2; UT2
UniProt Entry Name
UT2_HUMAN
NCBI Description
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
SLC14A2: Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism. Belongs to the urea transporter family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 18q12.1-q21.1
Cellular Component: membrane; apical plasma membrane; integral to membrane; plasma membrane
Molecular Function: protein binding; urea transmembrane transporter activity; cell adhesion molecule binding
Biological Process: urea transport; transmembrane transport
Research Articles on SLC14A2
Similar Products
Product Notes
The SLC14A2 slc14a2 (Catalog #AAA621227) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Urea Transporter A1 (Slc14a2. Solute carrier family 14 (urea transporter), member 2, Slc14a2T, Solute carrier family 14 member 2, Urea transporter, kidney, Urea transporter 2, UrT1-C, UrT1-D, Ut2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Urea Transporter A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Suitable for use in Western Blot and Immunocytochemistry. Dilution: Western Blot: 1:1000. 1ug/ml detected UT-A1 in 20 ug of rat kidney tissue lysate by colorimetric immunoblot analysis using IgG goat x rabbit (HRP) as the secondary antibody. Optimal diluitons to be determined by the researcher. Researchers should empirically determine the suitability of the SLC14A2 slc14a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Urea Transporter A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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