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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer using UPP2 Polyclonal Antibody at dilution of 1/35)

Rabbit anti-Human, Mouse UPP2 Polyclonal Antibody | anti-UPP2 antibody

UPP2 Polyclonal Antibody

Gene Names
UPP2; UP2; UPASE2; UDRPASE2
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
UPP2; Polyclonal Antibody; UPP2 Polyclonal Antibody; UP2; UPASE2; UDRPASE2; anti-UPP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
5.3mg/ml (varies by lot)
Sequence Length
374
Applicable Applications for anti-UPP2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-2000
IHC: 1:30-150
WB: 1:200-1000
Immunogen
Synthetic peptide of human UPP2
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer using UPP2 Polyclonal Antibody at dilution of 1/35)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer using UPP2 Polyclonal Antibody at dilution of 1/35)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast cancer using UPP2 Polyclonal Antibody at dilution of 1/35)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer using UPP2 Polyclonal Antibody at dilution of 1/35)
Related Product Information for anti-UPP2 antibody
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2 (')-deoxyuridine as substrates.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36 kDa
NCBI Official Full Name
uridine phosphorylase 2 isoform b
NCBI Official Synonym Full Names
uridine phosphorylase 2
NCBI Official Symbol
UPP2
NCBI Official Synonym Symbols
UP2; UPASE2; UDRPASE2
NCBI Protein Information
uridine phosphorylase 2
UniProt Protein Name
Uridine phosphorylase 2
Protein Family
UniProt Gene Name
UPP2
UniProt Synonym Gene Names
UPase 2; UrdPase 2
UniProt Entry Name
UPP2_HUMAN

Uniprot Description

UPP2: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. Belongs to the PNP/UDP phosphorylase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.4.2.3; Nucleotide Metabolism - pyrimidine; Phosphorylase; Transferase; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 2q24.1

Cellular Component: cytosol; type III intermediate filament

Molecular Function: protein binding; uridine phosphorylase activity

Biological Process: pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage

Research Articles on UPP2

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Product Notes

The UPP2 upp2 (Catalog #AAA2542938) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UPP2 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's UPP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-2000 IHC: 1:30-150 WB: 1:200-1000. Researchers should empirically determine the suitability of the UPP2 upp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UPP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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