Human Netrin receptor UNC5D (UNC5D) ELISA Kit | UNC5D elisa kit

Human Netrin receptor UNC5D (UNC5D) ELISA Kit

Cat. Num. AAA167519

• Gene Names: UNC5D; Unc5h4; PRO34692
• Reactivity: Human
• Synonyms: Netrin receptor UNC5D (UNC5D); Human Netrin receptor UNC5D (UNC5D) ELISA Kit; UNC5D elisa kit

• Reactivity: Human
• Sequence Length: 953

• Samples: Serum, plasma, cell culture supernates, cell lysates, tissue homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.1ng/ml - 30ng/ml
• Sensitivity: 0.06ng/ml
• Intra-Assay: CV<8%
• Inter-Assay: CV<10%
• Preparation and Storage: Store at 2 to 8 degree C for 6 months.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for UNC5D elisa kit

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Netrin Receptor UNC5D (also known as UNC5D) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.

Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human UNC5D antibody. UNC5D present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human UNC5D Antibody is added and binds to UNC5D in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated UNC5D antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human UNC5D. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.

NCBI and Uniprot Product Information

• NCBI GI #: 209977117
• NCBI GeneID: 137970
• NCBI Accession #: NP_543148.2
• NCBI GenBank Nucleotide #: NM_080872.3
• UniProt Accession #: Q6UXZ4; Q8WYP7
• Molecular Weight: 105,491 Da
• NCBI Official Full Name: netrin receptor UNC5D isoform 1
• NCBI Official Synonym Full Names: unc-5 netrin receptor D
• NCBI Official Symbol: UNC5D
• NCBI Official Synonym Symbols: Unc5h4; PRO34692
• NCBI Protein Information: netrin receptor UNC5D
• UniProt Protein Name: Netrin receptor UNC5D
• Protein Family: Netrin receptor
• UniProt Gene Name: UNC5D

Uniprot Description

Receptor for the netrin NTN4 that promotes neuronal cell survival (). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (). May play a role in apoptosis in response to DNA damage (PubMed:24691657). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell ().