Western Blot (WB)
(UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).)
Rabbit anti-Human UNC5D Polyclonal Antibody | anti-UNC5D antibody
UNC5D, ID (UNC5D, KIAA1777, UNC5H4, Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).)
Western Blot (WB)
(UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
Function: Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand
By similarity.
Subunit structure: Interacts with the cytoplasmic part of DCC
By similarity.
Subcellular location: Membrane; Single-pass type I membrane protein
By similarity.
Post-translational modification: Phosphorylated on cytoplasmic tyrosine residues
By similarity.Proteolytically cleaved by caspases during apoptosis. The cleavage does not take place when the receptor is associated with netrin ligand. Its cleavage by caspases is required to induce apoptosis
By similarity.
Sequence similarities: Belongs to the unc-5 family.Contains 1 death domain.Contains 1 Ig-like (immunoglobulin-like) domain.Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 2 TSP type-1 domains.Contains 1 ZU5 domain.
Research Articles on UNC5D
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Product Notes
The UNC5D unc5d (Catalog #AAA646002) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UNC5D, ID (UNC5D, KIAA1777, UNC5H4, Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UNC5D can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the UNC5D unc5d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UNC5D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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