Rabbit anti-Human, Mouse UHRF1BP1 Polyclonal Antibody | anti-UHRF1BP1 antibody

UHRF1BP1 Antibody

Cat. Num. AAA150635

• Gene Names: UHRF1BP1; ICBP90; C6orf107; dJ349A12.1
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: UHRF1BP1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: UHRF1BP1; Polyclonal Antibody; UHRF1BP1 Antibody; ICBP90; C6orf107; dJ349A12.1; UHRF1-binding protein 1; ICBP90-binding protein 1; UHRF1 binding protein 1; anti-UHRF1BP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L
• Purity/Purification: UHRF1BP1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1440

• Applicable Applications for anti-UHRF1BP1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: UHRF1BP1 antibody can be used for detection of UHRF1BP1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
• Conjugate: Unconjugated
• Immunogen: UHRF1BP1 antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1.
• Buffer: UHRF1BP1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: UHRF1BP1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of UHRF1BP1 in mouse kidney tissue lysate with UHRF1BP1 antibody at (A) 1 and (B) 2 μg/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of UHRF1BP1 in human kidney tissue with UHRF1BP1 antibody at 2.5 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of UHRF1BP1 in human kidney tissue with UHRF1BP1 antibody at 20 μg/mL.)

Related Product Information for anti-UHRF1BP1 antibody

UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.

NCBI and Uniprot Product Information

• NCBI GI #: 134152667
• NCBI GeneID: 54887
• NCBI Accession #: NP_060224
• NCBI GenBank Nucleotide #: NM_017754.3
• UniProt Accession #: Q6BDS2; Q9NXE0
• Molecular Weight: 159,485 Da
• NCBI Official Full Name: UHRF1-binding protein 1
• NCBI Official Synonym Full Names: UHRF1 binding protein 1
• NCBI Official Symbol: UHRF1BP1
• NCBI Official Synonym Symbols: ICBP90; C6orf107; dJ349A12.1
• NCBI Protein Information: UHRF1-binding protein 1; ICBP90 binding protein 1; ICBP90-binding protein 1; UHRF1 (ICBP90) binding protein 1; ubiquitin-like containing PHD and RING finger domains 1-binding protein 1
• UniProt Protein Name: UHRF1-binding protein 1
• Protein Family: UHRF1-binding protein
• UniProt Gene Name: UHRF1BP1
• UniProt Synonym Gene Names: C6orf107
• UniProt Entry Name: URFB1_HUMAN

Uniprot Description

UHRF1BP1: May act as a negative regulator of cell growth.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6p21

Molecular Function: identical protein binding; protein binding; histone deacetylase binding