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Goat UBP1 Polyclonal Antibody | anti-UBP1 antibody

Goat anti-UBP1 Antibody

Gene Names
UBP1; LBP1A; LBP1B; LBP-1B; LBP-1a
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
UBP1; Polyclonal Antibody; Goat anti-UBP1 Antibody; upstream binding protein 1 (LBP-1a); DKFZp686L1745; LBP-1B; LBP-1a; LBP1A; LBP1B; transcription factor LBP-1; DKFZp686L1745 antibody; LBP1A antibody; LBP-1a antibody; LBP1B antibody; LBP-1B antibody; transcription factor LBP-1 antibody; upstream binding protein 1 (LBP-1a) antibody; UBP1 antibody; anti-UBP1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
PNHQGDGASQTSGE
Sequence Length
540
Applicable Applications for anti-UBP1 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Preliminary experiments in Human Kidney, Human Adrenal gland, HeLa and HepG2 lysates gave no specific signal but low background (at antibody concentration up to 2ug/ml).
Immunogen
Peptide with sequence C-PNHQGDGASQTSGE, from the internal region of the protein sequence according to NP_055332.3; NP_001121632.1.
Epitope
Internal region
Note
Reported variants represent identical protein: NP_001121633.1, NP_055332.3.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,453 Da
NCBI Official Full Name
upstream-binding protein 1 isoform LBP-1b
NCBI Official Synonym Full Names
upstream binding protein 1 (LBP-1a)
NCBI Official Symbol
UBP1
NCBI Official Synonym Symbols
LBP1A; LBP1B; LBP-1B; LBP-1a
NCBI Protein Information
upstream-binding protein 1
UniProt Protein Name
Upstream-binding protein 1
Protein Family
UniProt Gene Name
UBP1
UniProt Synonym Gene Names
LBP1
UniProt Entry Name
UBIP1_HUMAN

Uniprot Description

UBP1: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. Belongs to the grh/CP2 family. CP2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity

Biological Process: angiogenesis; negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral genome replication

Research Articles on UBP1

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Product Notes

The UBP1 ubp1 (Catalog #AAA422247) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-UBP1 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's UBP1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Preliminary experiments in Human Kidney, Human Adrenal gland, HeLa and HepG2 lysates gave no specific signal but low background (at antibody concentration up to 2ug/ml). Researchers should empirically determine the suitability of the UBP1 ubp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PNHQGDGASQ TSGE. It is sometimes possible for the material contained within the vial of "UBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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