Western Blot (WB)
(Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit TYW4 Polyclonal Antibody | anti-LCMT2 antibody
TYW4 Antibody
Western Blot (WB)
(Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of TYW4 in rat brain tissue lysate with TYW4 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of TYW4 in mouse brain tissue with TYW4 antibody at 5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of TYW1 in mouse brain tissue with TYW1 antibody at 20 μg/mL.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008]
Uniprot Description
LCMT2: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha- leucine ester residues. Belongs to the methyltransferase superfamily. LCMT family.
Protein type: Lipid Metabolism - androgen and estrogen; Amino Acid Metabolism - histidine; Methyltransferase; Amino Acid Metabolism - tyrosine; EC 2.3.1.231; EC 2.1.1.290; Other Amino Acids Metabolism - selenoamino acid
Chromosomal Location of Human Ortholog: 15q15.3
Molecular Function: methyltransferase activity; protein binding
Biological Process: methylation; tRNA processing
Research Articles on LCMT2
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Product Notes
The LCMT2 lcmt2 (Catalog #AAA150518) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TYW4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TYW4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). TYW4 antibody can be used for detection of TYW4 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the LCMT2 lcmt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TYW4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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