Goat TXNDC11 Polyclonal Antibody | anti-TXNDC11 antibody

Goat anti-TXNDC11 (aa113-126) Antibody

Cat. Num. AAA422889

• Gene Names: TXNDC11; EFP1
• Reactivity: Tested: Human; Expected from sequence similarity: Human
• Applications: ELISA, Western Blot
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: TXNDC11; Polyclonal Antibody; Goat anti-TXNDC11 (aa113-126) Antibody; thioredoxin domain containing 11; EFP1; EF-hand binding protein 1; EF-hand-binding protein 1; thioredoxin domain-containing protein 11; TXNDC11 antibody; thioredoxin domain containing 11 antibody; EFP1 antibody; EF-hand binding protein 1 antibody; EF-hand-binding protein 1 antibody; thioredoxin domain-containing protein 11 antibody; TXNDC11 (aa113-126); anti-TXNDC11 antibody

• Host: Goat
• Reactivity: Tested: Human; Expected from sequence similarity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: QLDYAEYVRRDSE
• Sequence Length: 958

• Applicable Applications for anti-TXNDC11 antibody: Peptide ELISA (EIA), Western Blot (WB)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 16000.; Western Blot: Approx 100kDa band observed in Human Spleen and Thymus lysates (calculated MW of 108kDa according to NP_056998.4). Recommended concentration: 1-3ug/ml.
• Immunogen: Peptide with sequence C-QLDYAEYVRRDSE, from the internal region of the protein sequence according to NP_056998.4.
• Epitope: Internal region
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

Western Blot (WB)

((1ug/ml) staining of Human Thymus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

• NCBI GI #: 54633317
• NCBI GeneID: 51061
• NCBI Accession #: NP_056998.4
• NCBI GenBank Nucleotide #: NM_015914.6
• Molecular Weight: 30,375 Da
• NCBI Official Full Name: thioredoxin domain-containing protein 11 isoform 2
• NCBI Official Synonym Full Names: thioredoxin domain containing 11
• NCBI Official Symbol: TXNDC11
• NCBI Official Synonym Symbols: EFP1
• NCBI Protein Information: thioredoxin domain-containing protein 11
• UniProt Protein Name: Thioredoxin domain-containing protein 11
• Protein Family: Thioredoxin domain-containing protein
• UniProt Gene Name: TXNDC11
• UniProt Synonym Gene Names: EFP1
• UniProt Entry Name: TXD11_HUMAN

Uniprot Description

TXNDC11: May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Belongs to the protein disulfide isomerase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.13

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: protein binding; protein disulfide isomerase activity

Biological Process: cell redox homeostasis; protein folding