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Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded xenograft using TTLL1 antibody at a dilution of 1:500)

Rabbit TTLL1 Polyclonal Antibody | anti-TTLL1 antibody

TTLL1 antibody

Applications
Immunohistochemistry, Western Blot
Purity
TTLL1 antibody was purified by antigen-affinity chromatography
Synonyms
TTLL1; Polyclonal Antibody; TTLL1 antibody; Polyclonal TTLL1; Anti-TTLL1; TTLL-1; TTLL 1; tubulin--tyrosine ligase-like protein 1; PGs3; HS323M22B; C22orf7; tubulin-tyrosine ligase; tubulin polyglutamylase complex subunit 3; probable tubulin polyglutamylase TTLL1; catalytic subunit of neural tubulin polyglutamylase; tubulin tyrosine ligase-like family member 1; anti-TTLL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
TTLL1 antibody was purified by antigen-affinity chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
423
Applicable Applications for anti-TTLL1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100-1:500
WB: 1:500-1:3000
Biological Significance
Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin.
Cross-Reactivity
Human
Immunogen
TTLL1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 208 of TTLL1
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemical staining of paraffin-embedded xenograft using TTLL1 antibody at a dilution of 1:500)

Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded xenograft using TTLL1 antibody at a dilution of 1:500)

Western Blot (WB)

(Western blot analysis of 30 ug of whole cell lysate (A: Hep G2) using a 10 % SDS PAGE gel and TTLL1 antibody at a dilution of 1:1000)

Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A: Hep G2) using a 10 % SDS PAGE gel and TTLL1 antibody at a dilution of 1:1000)
Related Product Information for anti-TTLL1 antibody
Affinity purified Rabbit polyclonal TTLL1 antibody
Product Categories/Family for anti-TTLL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
49 kDa
NCBI Official Full Name
TTLL1
UniProt Protein Name
Probable tubulin polyglutamylase TTLL1
UniProt Gene Name
TTLL1
UniProt Synonym Gene Names
C22orf7; PGs3
UniProt Entry Name
TTLL1_HUMAN

Uniprot Description

TTLL1: Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Belongs to the tubulin polyglutamylase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; EC 6.-.-.-; Cell cycle regulation; Ligase

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: microtubule; cytoplasm

Biological Process: protein polyglutamylation; axoneme biogenesis

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Product Notes

The TTLL1 ttll1 (Catalog #AAA837382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TTLL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100-1:500 WB: 1:500-1:3000. Researchers should empirically determine the suitability of the TTLL1 ttll1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TTLL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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