Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS7605239 (TRMT2B antibody) at dilution of 1:50)
Rabbit anti-Human TRMT2B Polyclonal Antibody | anti-TRMT2B antibody
TRMT2B Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS7605239 (TRMT2B antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS7605239 (TRMT2B antibody) at dilution of 1:50)
Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7605239 (TRMT2B antibody) at dilution of 1:300)
Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7605239 (TRMT2B antibody) at dilution of 1:300)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]
Uniprot Description
TRMT2B: Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation. Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.1.1.35; Methyltransferase
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: mitochondrion
Molecular Function: protein binding; S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity
Biological Process: RNA methylation; tRNA processing
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Product Notes
The TRMT2B trmt2b (Catalog #AAA7605239) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRMT2B Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRMT2B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TRMT2B trmt2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRMT2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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