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SDS-Page

PRRX1 recombinant protein

PRRX1, 1-217aa, Human, His tag, E Coli

Gene Names
PRRX1; PMX1; PRX1; AGOTC; PHOX1; PRX-1
Applications
SDS-Page
Purity
> 85% by SDS-PAGE
Synonyms
PRRX1; 1-217aa; Human; His tag; E Coli; Paired related homeobox 1; AGOTC; PHOX1; PMX1; PRX-1; PRX1; PRRX1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 85% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Concentration
0.25mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMTSSYG HVLERQPALG GRLDSPGNLD TLQAKKNFSV SHLLDLEEAG DMVAAQADEN VGEAGRSLLE SPGLTSGSDT PQQDNDQLNS EEKKKRKQRR NRTTFNSSQL QALERVFERT HYPDAFVRED LARRVNLTEA RVQVWFQNRR AKFRRNERAM LANKNASLLK SYSGDVTAVE QPIVPRPAPR PTDYLSWGTA SPYRSSSLPR CCLHEGLHNG F
Sequence Length
217
Applicable Applications for PRRX1 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for PRRX1 recombinant protein
Paired related homeobox 1, also known as PRRX1, acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer. Recombinant human PRRX1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for PRRX1 recombinant protein
References
Grueneberg D.A., et al. (1992) Science. 257:1089-1095; Sergi C., et al. (2011) Clin. Genet. 79:293-295;

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26.9 kDa (241aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
NCBI Official Full Name
paired mesoderm homeobox protein 1 isoform pmx-1a
NCBI Official Synonym Full Names
paired related homeobox 1
NCBI Official Symbol
PRRX1
NCBI Official Synonym Symbols
PMX1; PRX1; AGOTC; PHOX1; PRX-1
NCBI Protein Information
paired mesoderm homeobox protein 1
UniProt Protein Name
Paired mesoderm homeobox protein 1
UniProt Gene Name
PRRX1
UniProt Synonym Gene Names
PMX1; PRX-1

NCBI Description

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008]

Uniprot Description

Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer ().

Research Articles on PRRX1

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Product Notes

The PRRX1 prrx1 (Catalog #AAA205374) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's PRRX1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the PRRX1 prrx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSHMTSSYG HVLERQPALG GRLDSPGNLD TLQAKKNFSV SHLLDLEEAG DMVAAQADEN VGEAGRSLLE SPGLTSGSDT PQQDNDQLNS EEKKKRKQRR NRTTFNSSQL QALERVFERT HYPDAFVRED LARRVNLTEA RVQVWFQNRR AKFRRNERAM LANKNASLLK SYSGDVTAVE QPIVPRPAPR PTDYLSWGTA SPYRSSSLPR CCLHEGLHNG F. It is sometimes possible for the material contained within the vial of "PRRX1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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