Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Anti-TRH Receptor antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit TRH Receptor / TRHR Polyclonal Antibody | anti-TRHR antibody

Rabbit Polyclonal (IgG) to Human TRH Receptor / TRHR

Gene Names
TRHR; TRH-R
Reactivity
Bovine, Chimpanzee, Dog, Human, Monkey, Mouse, Opossum, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Protein G Purified
Synonyms
TRH Receptor / TRHR; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human TRH Receptor / TRHR; Anti-TRH Receptor / TRHR Antibody (aa350-400) IHC-plus; TRHR; TRH receptor; TRH-R; Thyroliberin receptor; Human TRH Receptor; anti-TRHR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Bovine, Chimpanzee, Dog, Human, Monkey, Mouse, Opossum, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
A portion of amino acids 350-400 of human TRH-R protein
Purity/Purification
Protein G Purified
Form/Format
PBS, 0.2% gelatin, 0.05% sodium azide.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
398
Applicable Applications for anti-TRHR antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes
IHC-P (10 ug/ml), WB (0.5 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic peptide from human TRHR.
Immunogen Type
Synthetic peptide
Immunogen
TRH Receptor / TRHR antibody was raised against synthetic peptide from human TRHR.
Antigen Modification
aa350-400
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-TRH Receptor antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-TRH Receptor antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of human TRH-R in human brain lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 0.5 ug/ml.)

Western Blot (WB) (Western blot of human TRH-R in human brain lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 0.5 ug/ml.)
Related Product Information for anti-TRHR antibody
The thyrotropin-releasing hormone receptor (TRH-R), a Releasing Hormone Receptor, is activated by thyrotropin-releasing hormone. TRH-R may play a role in the etiopathogenesis of essential hypertension.
Product Categories/Family for anti-TRHR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,085 Da
NCBI Official Full Name
thyrotropin-releasing hormone receptor
NCBI Official Synonym Full Names
thyrotropin-releasing hormone receptor
NCBI Official Symbol
TRHR
NCBI Official Synonym Symbols
TRH-R
NCBI Protein Information
thyrotropin-releasing hormone receptor; thyroliberin receptor
UniProt Protein Name
Thyrotropin-releasing hormone receptor
UniProt Gene Name
TRHR
UniProt Synonym Gene Names
TRH-R
UniProt Entry Name
TRFR_HUMAN

NCBI Description

This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]

Uniprot Description

TRHR: Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q23

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: thyrotropin-releasing hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on TRHR

Similar Products

Product Notes

The TRHR trhr (Catalog #AAA241679) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human TRH Receptor / TRHR reacts with Bovine, Chimpanzee, Dog, Human, Monkey, Mouse, Opossum, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TRH Receptor / TRHR can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (10 ug/ml), WB (0.5 - 1 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the TRHR trhr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRH Receptor / TRHR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.