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Immunohistochemistry (IHC) (Anti-TRH Receptor / TRHR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit TRH Receptor / TRHR Polyclonal Antibody | anti-TRHR antibody

Rabbit Polyclonal to Human TRH Receptor / TRHR

Gene Names
TRHR; TRH-R
Reactivity
Gibbon, Dog, Gorilla, Horse, Human, Monkey, Sheep
Predicted Reactivity: Rat, Pig (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
TRH Receptor / TRHR; Polyclonal Antibody; Rabbit Polyclonal to Human TRH Receptor / TRHR; Anti-TRH Receptor / TRHR Antibody (C-Terminus) IHC-plus; TRHR; TRH receptor; TRH-R; Thyroliberin receptor; Human TRH Receptor; anti-TRHR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Dog, Gorilla, Horse, Human, Monkey, Sheep
Predicted Reactivity: Rat, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human TRH Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
398
Applicable Applications for anti-TRHR antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (16 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from C-terminus of human TRH Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Sheep, Dog, Panda, Horse (100%); Rat, Elephant, Pig (94%).
Immunogen Type
Synthetic peptide
Immunogen
TRH Receptor / TRHR antibody was raised against synthetic 17 amino acid peptide from C-terminus of human TRH Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Sheep, Dog, Panda, Horse (100%); Rat, Elephant, Pig (94%); Mouse, Bovine, Rabbit, Opossum (88%); Hamster, Turkey, Medaka (82%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-TRH Receptor / TRHR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-TRH Receptor / TRHR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-TRH Receptor / TRHR antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-TRH Receptor / TRHR antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-TRH Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-TRH Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-TRHR antibody
The thyrotropin-releasing hormone receptor (TRH-R), a Releasing Hormone Receptor, is activated by thyrotropin-releasing hormone. TRH-R may play a role in the etiopathogenesis of essential hypertension.
Product Categories/Family for anti-TRHR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,085 Da
NCBI Official Full Name
thyrotropin-releasing hormone receptor
NCBI Official Synonym Full Names
thyrotropin-releasing hormone receptor
NCBI Official Symbol
TRHR
NCBI Official Synonym Symbols
TRH-R
NCBI Protein Information
thyrotropin-releasing hormone receptor; thyroliberin receptor
UniProt Protein Name
Thyrotropin-releasing hormone receptor
UniProt Gene Name
TRHR
UniProt Synonym Gene Names
TRH-R
UniProt Entry Name
TRFR_HUMAN

NCBI Description

This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]

Uniprot Description

TRHR: Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 8q23

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: thyrotropin-releasing hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on TRHR

Similar Products

Product Notes

The TRHR trhr (Catalog #AAA242736) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human TRH Receptor / TRHR reacts with Gibbon, Dog, Gorilla, Horse, Human, Monkey, Sheep Predicted Reactivity: Rat, Pig (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's TRH Receptor / TRHR can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (16 ug/ml). Researchers should empirically determine the suitability of the TRHR trhr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRH Receptor / TRHR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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