Immunohistochemistry (IHC)
(Immunochemical staining of mouse TFRC in mouse small intestine with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Mouse Transferrin Receptor/TFRC Polyclonal Antibody | anti-TFRC antibody
Anti-Transferrin Receptor/TFRC Antibody, Rabbit Polyclonal
Gene Names
Tfrc; TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; Mtvr-1; AI195355; AI426448; AU015758; 2610028K12Rik; E430033M20Rik
Reactivity
Mouse
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
Transferrin Receptor/TFRC; Polyclonal Antibody; Anti-Transferrin Receptor/TFRC Antibody; Rabbit Polyclonal; TFRC/CD71 Antibody; Rabbit PAb; Antigen Affinity Purified; transferrin receptor; Anti-2610028K12Rik Antibody; Anti-AI195355 Antibody; Anti-AI426448 Antibody; Anti-AU015758 Antibody; Anti-CD71 Antibody; Anti-E430033M20Rik Antibody; Anti-Mtvr-1 Antibody; Anti-Mtvr1 Antibody; Anti-p90 Antibody; Anti-TFR Antibody; Anti-TFR1 Antibody; Anti-TR Antibody; Anti-Trfr Antibody; anti-TFRC antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse TFRC/CD71
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-TFRC antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:500-1:2000
IHC-P: 1:500-1:2000
Immunogen
Recombinant Mouse TFRC/CD71 Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Mouse TFRC/CD71 (rM TFRC/CD71). TFRC/CD71 specific IgG was purified by Mouse TFRC/CD71 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of mouse TFRC in mouse small intestine with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse TFRC in mouse small intestine with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-TFRC antibody
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC/CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC/CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC/CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential and therapeutic target.
References
Douabin-Gicquel V., et al., 2001, Hum. Genet. 109:393-401. Ryschich, E. et al., 2004, Eur J Cancer. 40 (9):1418-22. Tosoni D., et al., 2005, Cell 123:875-888. Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
transferrin receptor protein 1
NCBI Official Synonym Full Names
transferrin receptor
NCBI Official Symbol
Tfrc
NCBI Official Synonym Symbols
TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; Mtvr-1; AI195355; AI426448; AU015758; 2610028K12Rik; E430033M20Rik
NCBI Protein Information
transferrin receptor protein 1; OTTMUSP00000033382; mammary tumor virus receptor 1
UniProt Protein Name
Transferrin receptor protein 1
Protein Family
UniProt Entry Name
TFR1_MOUSE
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Product Notes
The TFRC (Catalog #AAA8112020) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Transferrin Receptor/TFRC Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Transferrin Receptor/TFRC can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the TFRC for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transferrin Receptor/TFRC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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