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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS969966 at dilution of 1:100)

Rabbit anti-Human TPSB2 Polyclonal Antibody | anti-TPSB2 antibody

TPSB2 Antibody

Gene Names
TPSAB1; TPS1; TPS2; TPSB1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%,Protein G purified
Synonyms
TPSB2; Polyclonal Antibody; TPSB2 Antibody; Tryptase beta-2; Tryptase-2; Tryptase II; TPS2; anti-TPSB2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
275
Applicable Applications for anti-TPSB2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
Recombinant human Tryptase beta-2 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS969966 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS969966 at dilution of 1:100)

Western Blot (WB)

(Western BlotPositive WB detected in: Rat liver tissue,Rat kidney tissue,Mouse liver tissue,Mouse kidney tissue,Mouse stomach tissueAll lanes: TPSB2 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 31 KDaObserved band size: 31 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: Rat liver tissue,Rat kidney tissue,Mouse liver tissue,Mouse kidney tissue,Mouse stomach tissueAll lanes: TPSB2 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 31 KDaObserved band size: 31 KDa)
Related Product Information for anti-TPSB2 antibody
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,515 Da
NCBI Official Full Name
tryptase alpha/beta-1
NCBI Official Synonym Full Names
tryptase alpha/beta 1
NCBI Official Symbol
TPSAB1
NCBI Official Synonym Symbols
TPS1; TPS2; TPSB1
NCBI Protein Information
tryptase alpha/beta-1
UniProt Protein Name
Tryptase beta-2
Protein Family
UniProt Gene Name
TPSB2
UniProt Synonym Gene Names
TPS2; Tryptase-2
UniProt Entry Name
TRYB2_HUMAN

NCBI Description

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]

Uniprot Description

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.

Research Articles on TPSB2

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Product Notes

The TPSB2 tpsb2 (Catalog #AAA969966) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TPSB2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TPSB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TPSB2 tpsb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TPSB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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