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Western Blot (WB) (Western Blot: Sample: Lane1: Mouse Heart Tissue; Lane2: Rat Heart Tissue.)

Rabbit anti-Rat Natriuretic Peptide Precursor A (NPPA) Polyclonal Antibody | anti-NPPA antibody

Natriuretic Peptide Precursor A (NPPA) Polyclonal Antibody

Gene Names
Nppa; ANF; ANP; Pnd; RATANF
Reactivity
Rat
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Antigen-specific affinity chromatography
Synonyms
Natriuretic Peptide Precursor A (NPPA); Polyclonal Antibody; Natriuretic Peptide Precursor A (NPPA) Polyclonal Antibody; Polyclonal Antibody to Natriuretic Peptide Precursor A (NPPA); ANH; ANF; PND; NPPA; CDD-ANF; Atrial Natriuretic Factor; Atrial Natriuretic Hormone; Atriopeptin; Natriuretic Peptide Precursor A; Prepronatriodilatin; Cardiodilatin-related peptide; anti-NPPA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against NPPA. It has been selected for its ability to recognize NPPA in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Sequence Length
153
Applicable Applications for anti-NPPA antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.5-2ug/mL
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Organism Species
Rat
Immunogen
Recombinant Natriuretic Peptide Precursor A (NPPA)
Cross Reactivity
Human, Mouse, Rat
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Lane1: Mouse Heart Tissue; Lane2: Rat Heart Tissue.)

Western Blot (WB) (Western Blot: Sample: Lane1: Mouse Heart Tissue; Lane2: Rat Heart Tissue.)

Western Blot (WB)

(Western Blot: Sample: Recombinant NPPA, Rat.)

Western Blot (WB) (Western Blot: Sample: Recombinant NPPA, Rat.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,556 Da
NCBI Official Full Name
natriuretic peptides A
NCBI Official Synonym Full Names
natriuretic peptide A
NCBI Official Symbol
Nppa
NCBI Official Synonym Symbols
ANF; ANP; Pnd; RATANF
NCBI Protein Information
natriuretic peptides A
UniProt Protein Name
Natriuretic peptides A
UniProt Gene Name
Nppa
UniProt Synonym Gene Names
ANF; ANP

NCBI Description

peptide involved in the control of fluid volume and vascular function [RGD, Feb 2006]

Uniprot Description

NPPA: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Defects in NPPA are the cause of familial atrial fibrillation type 6 (ATFB6). Atrial fibrillation is a common disorder of cardiac rhythm that is hereditary in a small subgroup of patients. It is characterized by disorganized atrial electrical activity, progressive deterioration of atrial electromechanical function and ineffective pumping of blood into the ventricles. It can be associated with palpitations, syncope, thromboembolic stroke, and congestive heart failure. Belongs to the natriuretic peptide family.

Protein type: Hormone; Secreted; Secreted, signal peptide

Research Articles on NPPA

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Product Notes

The NPPA nppa (Catalog #AAA2090418) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Natriuretic Peptide Precursor A (NPPA) Polyclonal Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Natriuretic Peptide Precursor A (NPPA) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunocytochemistry in formalin fixed cells: 5-20ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL Immunohistochemistry in paraffin section: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the NPPA nppa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Natriuretic Peptide Precursor A (NPPA), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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