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Western Blot (WB) (Western blotAll lanes: TMOD1 antibody at 1.85ug/mlLane 1: Mouse brain tissueLane 2: Mouse lung tissueLane 3: Hela whole cell lysateLane 4: K562 whole cell lysateLane 5: A549 whole cell lysateLane 6: MCF7 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 41,27 kDaObserved band size: 41 kDa)

Rabbit anti-Human, Mouse TMOD1 Polyclonal Antibody | anti-TMOD1 antibody

TMOD1 Antibody

Gene Names
TMOD1; TMOD; ETMOD; D9S57E
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
TMOD1; Polyclonal Antibody; TMOD1 Antibody; Tropomodulin-1; Erythrocyte tropomodulin; E-Tmod; D9S57E; TMOD; anti-TMOD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
359
Applicable Applications for anti-TMOD1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Tropomodulin-1 protein (1-359AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: TMOD1 antibody at 1.85ug/mlLane 1: Mouse brain tissueLane 2: Mouse lung tissueLane 3: Hela whole cell lysateLane 4: K562 whole cell lysateLane 5: A549 whole cell lysateLane 6: MCF7 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 41,27 kDaObserved band size: 41 kDa)

Western Blot (WB) (Western blotAll lanes: TMOD1 antibody at 1.85ug/mlLane 1: Mouse brain tissueLane 2: Mouse lung tissueLane 3: Hela whole cell lysateLane 4: K562 whole cell lysateLane 5: A549 whole cell lysateLane 6: MCF7 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 41,27 kDaObserved band size: 41 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart tissue using MBS7046520 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human heart tissue using MBS7046520 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7046520 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7046520 at dilution 1:100)
Related Product Information for anti-TMOD1 antibody
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,014 Da
NCBI Official Full Name
tropomodulin-1
NCBI Official Synonym Full Names
tropomodulin 1
NCBI Official Symbol
TMOD1
NCBI Official Synonym Symbols
TMOD; ETMOD; D9S57E
NCBI Protein Information
tropomodulin-1
UniProt Protein Name
Tropomodulin-1
Protein Family
UniProt Gene Name
TMOD1
UniProt Synonym Gene Names
D9S57E; TMOD; E-Tmod
UniProt Entry Name
TMOD1_HUMAN

NCBI Description

This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]

Uniprot Description

TMOD1: Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. Belongs to the tropomodulin family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Cell development/differentiation; Contractile

Chromosomal Location of Human Ortholog: 9q22.3

Cellular Component: cytosol; signalosome; striated muscle thin filament

Molecular Function: tropomyosin binding

Biological Process: actin filament organization; muscle contraction; muscle filament sliding; myofibril assembly

Research Articles on TMOD1

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Product Notes

The TMOD1 tmod1 (Catalog #AAA7046520) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMOD1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TMOD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TMOD1 tmod1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMOD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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