Western Blot (WB)
(TMM18 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TMM18 antibody detected the TMM18 protein (arrow).)
Rabbit TMM18 Polyclonal Antibody | anti-TMEM18 antibody
TMM18 Antibody (Center)
Reactivity
Mouse (Predicted Reactivity: Chicken)
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TMM18; Polyclonal Antibody; TMM18 Antibody (Center); Transmembrane protein 18; TMEM18; anti-TMEM18 antibody
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Chicken)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TMM18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the Central region of human TMM18.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.48 (varies by lot)
Sequence Positions
63-90
Sequence Length
127
Applicable Applications for anti-TMEM18 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(TMM18 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TMM18 antibody detected the TMM18 protein (arrow).)
Western Blot (WB)
(TMM18 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TMM18 antibody detected the TMM18 protein (arrow).)
Immunohistochemistry (IHC)
(TMM18 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TMM18 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(TMM18 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TMM18 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-TMEM18 antibody
TMM18 is a cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).
Product Categories/Family for anti-TMEM18 antibody
References
Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)
Holzapfel, C., et al. Int J Obes (Lond) 34(10):1538-1545(2010)
Holzapfel, C., et al. J Epidemiol Community Health (2010) In press :
Elks, C.E., et al. PLoS Med. 7 (5), E1000284 (2010) :
Scherag, A., et al. PLoS Genet. 6 (4), E1000916 (2010) :
Holzapfel, C., et al. Int J Obes (Lond) 34(10):1538-1545(2010)
Holzapfel, C., et al. J Epidemiol Community Health (2010) In press :
Elks, C.E., et al. PLoS Med. 7 (5), E1000284 (2010) :
Scherag, A., et al. PLoS Genet. 6 (4), E1000916 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16265
NCBI Official Full Name
transmembrane protein 18
NCBI Official Synonym Full Names
transmembrane protein 18
NCBI Official Symbol
TMEM18
NCBI Protein Information
transmembrane protein 18
UniProt Protein Name
Transmembrane protein 18
Protein Family
UniProt Gene Name
TMEM18
UniProt Entry Name
TMM18_HUMAN
Uniprot Description
TMEM18: Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC). Belongs to the TMEM18 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p25.3
Cellular Component: nuclear membrane; cytoplasm; integral to membrane
Molecular Function: DNA binding
Biological Process: cell migration; transcription, DNA-dependent
Research Articles on TMEM18
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Product Notes
The TMEM18 tmem18 (Catalog #AAA9214311) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 63-90. The TMM18 Antibody (Center) reacts with Mouse (Predicted Reactivity: Chicken) and may cross-react with other species as described in the data sheet. AAA Biotech's TMM18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the TMEM18 tmem18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMM18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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