Rabbit TMEM204 Polyclonal Antibody | anti-TMEM204 antibody

Rabbit Polyclonal to Human TMEM204

Cat. Num. AAA248129

• Gene Names: TMEM204; CLP24; C16orf30
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: TMEM204; Polyclonal Antibody; Rabbit Polyclonal to Human TMEM204; Anti-TMEM204 Antibody (C-Terminus) IHC-plus; C16orf30; Claudin-like protein 24; CLP24; Transmembrane protein 204; Human TMEM204; anti-TMEM204 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Human TMEM204. At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 226

• Applicable Applications for anti-TMEM204 antibody: Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IF (20 ug/ml), IHC-P (5 ug/ml), WB (1 ug/ml)
• Target Species: Human
• Immunogen Description: A 17 amino acid peptide near the carboxy terminus of human TMEM204 (GenBank accession No. NP_078876)
• Immunogen Type: Synthetic peptide
• Immunogen: TMEM204 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human TMEM204 (GenBank accession No. NP_078876)
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-TMEM204 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of TMEM204 in mouse brain tissue with TMEM204 antibody at 20 µg/mL.)

Western Blot (WB)

(Western blot analysis of TMEM204 in human brain tissue lysate with TMEM204 antibody at 1 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 112807182
• NCBI GeneID: 79652
• NCBI Accession #: NP_078876.2
• NCBI GenBank Nucleotide #: NM_024600.5
• UniProt Accession #: Q9BSN7; Q3KRC1; Q9H7G5; D3DU76
• Molecular Weight: 24,540 Da
• NCBI Official Full Name: transmembrane protein 204
• NCBI Official Synonym Full Names: transmembrane protein 204
• NCBI Official Symbol: TMEM204
• NCBI Official Synonym Symbols: CLP24; C16orf30
• NCBI Protein Information: transmembrane protein 204; claudin-like protein 24; claudin-like protein of 24 kDa
• UniProt Protein Name: Transmembrane protein 204
• Protein Family: Transmembrane protein
• UniProt Gene Name: TMEM204
• UniProt Synonym Gene Names: C16orf30; CLP24
• UniProt Entry Name: TM204_HUMAN

NCBI Description

C16ORF30 plays a role in cell adhesion and cellular permeability at adherens junctions (Kearsey et al., 2004 [PubMed 15206924]).[supplied by OMIM, Mar 2008]

Uniprot Description

TMEM204: Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: adherens junction; plasma membrane; integral to membrane

Biological Process: regulation of vascular endothelial growth factor receptor signaling pathway; smooth muscle cell differentiation; lymph vessel development