Western Blot (WB)
(Western blot analysis of TMEM204 in human brain tissue lysate with TMEM204 antibody at 1 μg/mL .)
Rabbit TMEM204 Polyclonal Antibody | anti-TMEM204 antibody
TMEM204 Antibody
Gene Names
TMEM204; CLP24; C16orf30
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
TMEM204 Antibody is affinity chromatography purified via peptide column.
Synonyms
TMEM204; Polyclonal Antibody; TMEM204 Antibody; CLP24; C16orf30; UNQ6509/PRO21434; Transmembrane protein 204; Claudin-like protein 24; transmembrane protein 204; anti-TMEM204 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms.
Purity/Purification
TMEM204 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
226
Applicable Applications for anti-TMEM204 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
TMEM204 antibody can be used for detection of TMEM204 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
TMEM204 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TMEM204.
Buffer
TMEM204 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TMEM204 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of TMEM204 in human brain tissue lysate with TMEM204 antibody at 1 μg/mL .)
Western Blot (WB)
(Western blot analysis of TMEM204 in human brain tissue lysate with TMEM204 antibody at 1 μg/mL .)
Immunohistochemistry (IHC)
(Immunohistochemistry of TMEM204 in mouse brain tissue with TMEM204 antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of TMEM204 in mouse brain tissue with TMEM204 antibody at 5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of TMEM204 in mouse brain tissue with TMEM204 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of TMEM204 in mouse brain tissue with TMEM204 antibody at 20 μg/mL.)
Related Product Information for anti-TMEM204 antibody
TMEM204 Antibody: Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24,540 Da
NCBI Official Full Name
transmembrane protein 204
NCBI Official Synonym Full Names
transmembrane protein 204
NCBI Official Symbol
TMEM204
NCBI Official Synonym Symbols
CLP24; C16orf30
NCBI Protein Information
transmembrane protein 204; claudin-like protein 24; claudin-like protein of 24 kDa
UniProt Protein Name
Transmembrane protein 204
Protein Family
UniProt Gene Name
TMEM204
UniProt Synonym Gene Names
C16orf30; CLP24
UniProt Entry Name
TM204_HUMAN
NCBI Description
C16ORF30 plays a role in cell adhesion and cellular permeability at adherens junctions (Kearsey et al., 2004 [PubMed 15206924]).[supplied by OMIM, Mar 2008]
Uniprot Description
TMEM204: Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: adherens junction; integral to membrane; plasma membrane
Biological Process: regulation of vascular endothelial growth factor receptor signaling pathway; smooth muscle cell differentiation; lymph vessel development
Research Articles on TMEM204
Similar Products
Product Notes
The TMEM204 tmem204 (Catalog #AAA151496) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM204 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM204 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). TMEM204 antibody can be used for detection of TMEM204 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the TMEM204 tmem204 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM204, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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