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Immunohistochemistry (IHC) (Anti-Vasohibin 1 / VASH1 antibody IHC staining of human prostate, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit Vasohibin 1 / VASH1 Polyclonal Antibody | anti-VASH1 antibody

Anti-Vasohibin 1 / VASH1 Antibody (C-Terminus) IHC-plus

Gene Names
VASH1; KIAA1036
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
Vasohibin 1 / VASH1; Polyclonal Antibody; Anti-Vasohibin 1 / VASH1 Antibody (C-Terminus) IHC-plus; Rabbit Polyclonal to Human Vasohibin 1 / VASH1; Human Vasohibin 1 / VASH1; VASH1; KIAA1036; VASH; Vasohibin 1; Vasohibin-1; anti-VASH1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
Human VASH1. VASH1 antibody is predicted to not cross-react with other vasohibin protein family members. At least two isoforms are known to exist; this antibody will recognize only the long isoform.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
365
Applicable Applications for anti-VASH1 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)
Immunogen
Vasohibin 1 / VASH1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human VASH1
Immunogen Description
A 19 amino acid peptide near the carboxy terminus of human VASH1
Immunogen Type
Synthetic peptide
Antigen Modification
C-Terminus
Target Species
Human
Preparation and Storage
Short term 4 degree C
Long term aliquot and store at -20 degree C
Avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-Vasohibin 1 / VASH1 antibody IHC staining of human prostate, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-Vasohibin 1 / VASH1 antibody IHC staining of human prostate, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunofluorescence (IF)

(Immunofluorescence of VASH1 in mouse brain tissue with VASH1 antibody at 20 µg/mL.)

Immunofluorescence (IF) (Immunofluorescence of VASH1 in mouse brain tissue with VASH1 antibody at 20 µg/mL.)

Western Blot (WB)

(Western blot analysis of VASH1 in human brain tissue lysate with VASH1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of VASH1 in human brain tissue lysate with VASH1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-VASH1 antibody
VASH1 Antibody, KIAA1036 Antibody, VASH Antibody, Vasohibin 1 Antibody, Vasohibin-1 Antibody Description: Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,845 Da
NCBI Official Full Name
vasohibin-1
NCBI Official Synonym Full Names
vasohibin 1
NCBI Official Symbol
VASH1
NCBI Official Synonym Symbols
KIAA1036
NCBI Protein Information
vasohibin-1
UniProt Protein Name
Vasohibin-1
Protein Family
UniProt Gene Name
VASH1
UniProt Synonym Gene Names
KIAA1036; VASH
UniProt Entry Name
VASH1_HUMAN

Uniprot Description

VASH1: Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity. Belongs to the vasohibin family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: apical part of cell; cytoplasm; endoplasmic reticulum; extracellular space

Molecular Function: protein binding

Biological Process: angiogenesis; cell cycle arrest; negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; negative regulation of endothelial cell proliferation; response to wounding

Research Articles on VASH1

Similar Products

Product Notes

The VASH1 vash1 (Catalog #AAA249715) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Vasohibin 1 / VASH1 Antibody (C-Terminus) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Vasohibin 1 / VASH1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). IF (20 ug/ml) IHC-P (10 ug/ml) WB (1 - 2 ug/ml). Researchers should empirically determine the suitability of the VASH1 vash1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vasohibin 1 / VASH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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