Immunohistochemistry (IHC)
(Immunochemical staining of human TMCC2 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human TMCC2 Polyclonal Antibody | anti-TMCC2 antibody
Anti-TMCC2 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
TMCC2; Polyclonal Antibody; Anti-TMCC2 Antibody; Rabbit Polyclonal; TMCC2 Antibody; Rabbit PAb; Antigen Affinity Purified; transmembrane and coiled-coil domain family 2; Anti-HUCEP11 Antibody; anti-TMCC2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human TMCC2
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-TMCC2 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human TMCC2 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human TMCC2 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human TMCC2 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human TMCC2 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-TMCC2 antibody
TMCC2 (Transmembrane And Coiled-Coil Domain Family 2, also known as HUCEP11) is a Protein Coding gene. The TMCC2 gene, located on 1q32.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. An important paralog of this gene is TMCC1. TMCC2 is a neuronal, predominantly ER-localized, protein that co-migrated with AbetaPP during native gel electrophoresis of rat brain extracts, and co-immunoprecipitated with AbetaPP from transfected human cell lysates. TMCC2 may be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE. 223 organisms have orthologs with the human gene TMCC2.
References
Zhang C, et al. (2014) Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum. PLoS One 9 (1): e85206.Soranzo N, et al. (2009) A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the haemgen consortium. Nat Genet 41 (11): 1182-1190.Hopkins PC, et al. (2011) The impact of a novel apolipoprotein e and amyloid-beta protein precursor-interacting protein on the production of amyloid-beta. J Alzheimers Dis 26 (2): 239-253.
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Product Notes
The TMCC2 (Catalog #AAA8109584) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TMCC2 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TMCC2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the TMCC2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMCC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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