Western Blot (WB)
(TLR8 Antibody (E972) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TLR8 antibody detected the TLR8 protein (arrow).)
Rabbit anti-Mouse TLR8 Polyclonal Antibody | anti-Tlr8 antibody
Mouse TLR8 Antibody (C-term)
Western Blot (WB)
(TLR8 Antibody (E972) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TLR8 antibody detected the TLR8 protein (arrow).)
Western Blot (WB)
(TLR8 Antibody (E972) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TLR8 antibody detected the TLR8 protein (arrow).)
Immunohistochemistry (IHC)
(Mouse TLR8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse TLR8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse TLR8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse TLR8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Medzhitov R and Janeway C, Cell. 1997. 91: 295.
NCBI and Uniprot Product Information
Uniprot Description
TLR8: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Belongs to the Toll-like receptor family.
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: membrane; integral to membrane; intracellular
Molecular Function: single-stranded RNA binding; DNA binding; double-stranded RNA binding; drug binding
Biological Process: I-kappaB kinase/NF-kappaB cascade; regulation of cytokine secretion; regulation of protein amino acid phosphorylation; immune system process; response to virus; microglial cell activation; positive regulation of interleukin-8 biosynthetic process; positive regulation of interferon-alpha biosynthetic process; toll-like receptor 8 signaling pathway; signal transduction; MyD88-dependent toll-like receptor signaling pathway; positive regulation of innate immune response; positive regulation of interferon-beta biosynthetic process; toll-like receptor signaling pathway; innate immune response; inflammatory response; defense response to virus; positive regulation of interferon-gamma biosynthetic process
Research Articles on Tlr8
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Product Notes
The Tlr8 tlr8 (Catalog #AAA9206170) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 957-987. The Mouse TLR8 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TLR8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Tlr8 tlr8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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