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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon using MBS7604945 (TINAG-Specific antibody) at dilution of 1:100)

Rabbit anti-Human, Mouse TINAG Polyclonal Antibody | anti-TINAG antibody

TINAG-Specific Rabbit Polyclonal

Gene Names
TINAG; TIN-AG
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
TINAG; Polyclonal Antibody; TINAG-Specific Rabbit Polyclonal; anti-TINAG antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
140
Applicable Applications for anti-TINAG antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Tubulointerstitial nephritis antigen
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon using MBS7604945 (TINAG-Specific antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon using MBS7604945 (TINAG-Specific antibody) at dilution of 1:100)

Western Blot (WB)

(mouse small intestine tissue were subjected to SDS PAGE followed by western blot with MBS7604945 (TINAG-Specific antibody) at dilution of 1:500)

Western Blot (WB) (mouse small intestine tissue were subjected to SDS PAGE followed by western blot with MBS7604945 (TINAG-Specific antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
38,724 Da
NCBI Official Full Name
TINAG protein
NCBI Official Synonym Full Names
tubulointerstitial nephritis antigen
NCBI Official Symbol
TINAG
NCBI Official Synonym Symbols
TIN-AG
NCBI Protein Information
tubulointerstitial nephritis antigen
UniProt Protein Name
Tubulointerstitial nephritis antigen
UniProt Gene Name
TINAG
UniProt Synonym Gene Names
TIN-Ag
UniProt Entry Name
TINAG_HUMAN

NCBI Description

This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis. [provided by RefSeq, Nov 2011]

Uniprot Description

TINAG: Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic peptidase C1 family protein. Belongs to the peptidase C1 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: basement membrane; extracellular space; lysosome

Molecular Function: cysteine-type endopeptidase activity; nucleotide binding; polysaccharide binding; scavenger receptor activity

Biological Process: cell adhesion; immune response; proteolysis involved in cellular protein catabolic process; receptor-mediated endocytosis

Research Articles on TINAG

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Product Notes

The TINAG tinag (Catalog #AAA7604945) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TINAG-Specific Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TINAG can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TINAG tinag for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TINAG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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