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Rabbit anti-Human TIFA Polyclonal Antibody | anti-TIFA antibody

TIFA Antibody

Gene Names
TIFA; T2BP; T6BP; TIFAA
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G Purified
Synonyms
TIFA; Polyclonal Antibody; TIFA Antibody; TRAF-interacting protein with FHA domain-containing protein A; T2BP; Putative MAPK-activating protein PM14; Putative NF-kappa-B-activating protein 20; TRAF2-binding protein; anti-TIFA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
184
Applicable Applications for anti-TIFA antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human TRAF-interacting protein with FHA domain-containing protein A protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-TIFA antibody
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,445 Da
NCBI Official Full Name
TRAF-interacting protein with FHA domain-containing protein A
NCBI Official Synonym Full Names
TRAF interacting protein with forkhead associated domain
NCBI Official Symbol
TIFA
NCBI Official Synonym Symbols
T2BP; T6BP; TIFAA
NCBI Protein Information
TRAF-interacting protein with FHA domain-containing protein A
UniProt Protein Name
TRAF-interacting protein with FHA domain-containing protein A
UniProt Gene Name
TIFA
UniProt Synonym Gene Names
T2BP
UniProt Entry Name
TIFA_HUMAN

Uniprot Description

TIFA: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: intracellular

Molecular Function: protein binding

Biological Process: I-kappaB kinase/NF-kappaB cascade

Research Articles on TIFA

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Product Notes

The TIFA tifa (Catalog #AAA1497121) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TIFA Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TIFA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the TIFA tifa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIFA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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