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Western Blot (WB) (All lanes: Thioredoxin, mitochondrial antibody at 3ug/mlLane 1:mouse liver tissueLane 2:rat brain tissueLane 3:mouse kidney tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 18kDaObserved band size: 18kDa)

Rabbit Thioredoxin Polyclonal Antibody | anti-TXN2 antibody

Rabbit anti-human Thioredoxin, mitochondrial polyclonal Antibody(TXN2)

Gene Names
TXN2; MTRX; TRX2; MT-TRX
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Thioredoxin; Polyclonal Antibody; Rabbit anti-human Thioredoxin; mitochondrial polyclonal Antibody(TXN2); MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2; anti-TXN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
166
Applicable Applications for anti-TXN2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:500-5000
IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Thioredoxin, mitochondrial protein (1-166aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22980 / sc-50336 / sc-50336
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(All lanes: Thioredoxin, mitochondrial antibody at 3ug/mlLane 1:mouse liver tissueLane 2:rat brain tissueLane 3:mouse kidney tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 18kDaObserved band size: 18kDa)

Western Blot (WB) (All lanes: Thioredoxin, mitochondrial antibody at 3ug/mlLane 1:mouse liver tissueLane 2:rat brain tissueLane 3:mouse kidney tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 18kDaObserved band size: 18kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human tonsil using MBS1494888 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human tonsil using MBS1494888 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rectum using MBS1494888 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rectum using MBS1494888 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreas using MBS1494888 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreas using MBS1494888 at dilution 1:100)
Related Product Information for anti-TXN2 antibody
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,383 Da
NCBI Official Full Name
thioredoxin, mitochondrial
NCBI Official Synonym Full Names
thioredoxin 2
NCBI Official Symbol
TXN2
NCBI Official Synonym Symbols
MTRX; TRX2; MT-TRX
NCBI Protein Information
thioredoxin, mitochondrial
UniProt Protein Name
Thioredoxin, mitochondrial
Protein Family
UniProt Gene Name
TXN2
UniProt Synonym Gene Names
TRX2; MTRX; Mt-Trx
UniProt Entry Name
THIOM_HUMAN

NCBI Description

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008]

Uniprot Description

TXN2: Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. Belongs to the thioredoxin family.

Protein type: Oxidoreductase

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cell soma; dendrite; mitochondrial matrix; mitochondrion; nucleolus

Molecular Function: oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; peptide-methionine (R)-S-oxide reductase activity; peptide-methionine-(S)-S-oxide reductase activity; protein binding; protein complex binding; protein disulfide oxidoreductase activity

Biological Process: cell redox homeostasis; cellular response to nutrient levels; glycerol ether metabolic process; protein folding; response to axon injury; response to drug; response to glucose stimulus; response to hormone stimulus; response to hypoxia; response to nutrient; response to organic cyclic substance; response to reactive oxygen species; sulfate assimilation

Research Articles on TXN2

Similar Products

Product Notes

The TXN2 txn2 (Catalog #AAA1494888) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Thioredoxin, mitochondrial polyclonal Antibody(TXN2) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Thioredoxin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-5000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the TXN2 txn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thioredoxin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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