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Immunohistochemistry (IHC) (Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit TFB1/GTF2H1 Polyclonal Antibody | anti-TFB1/GTF2H1 antibody

Anti-TFB1/GTF2H1 Antibody (aa32-81)

Gene Names
GTF2H1; P62; BTF2; TFB1; TFIIH
Reactivity
Human
Predicted: Mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
TFB1/GTF2H1; Polyclonal Antibody; Anti-TFB1/GTF2H1 Antibody (aa32-81); Rabbit Polyclonal to Human TFB1/GTF2H1; GTF2H1; BTF2; BTF2 p62; p62; TFB1; TFIIH; anti-TFB1/GTF2H1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
TF2H1 Antibodyantibody detects endogenous levels of TF2H1.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Sequence Length
548
Applicable Applications for anti-TFB1/GTF2H1 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:10000
IHC-P: 1:50
WB: 1:500-1:1000
Immunogen
Synthetic peptide from human TF2H1 (aa32-81).
Conjugation
Unconjugated
Epitope
aa32-81
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB)

(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB) (Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot of the lysates from HepG2 cells using TF2H1 antibody.)

Western Blot (WB) (Western blot of the lysates from HepG2 cells using TF2H1 antibody.)
Related Product Information for anti-TFB1/GTF2H1 antibody
Component of the core-TFIIH basal transcription factor involved innucleotide excision repair (NER) of DNA and , when complexed to CAK, inRNA transcription by RNA polymerase II.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,738 Da
NCBI Official Full Name
general transcription factor IIH subunit 1
NCBI Official Synonym Full Names
general transcription factor IIH subunit 1
NCBI Official Symbol
GTF2H1
NCBI Official Synonym Symbols
P62; BTF2; TFB1; TFIIH
NCBI Protein Information
general transcription factor IIH subunit 1
UniProt Protein Name
General transcription factor IIH subunit 1
UniProt Gene Name
GTF2H1
UniProt Synonym Gene Names
BTF2; BTF2 p62

Uniprot Description

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.

Research Articles on TFB1/GTF2H1

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Product Notes

The TFB1/GTF2H1 gtf2h1 (Catalog #AAA2401228) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TFB1/GTF2H1 Antibody (aa32-81) reacts with Human Predicted: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TFB1/GTF2H1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:10000 IHC-P: 1:50 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the TFB1/GTF2H1 gtf2h1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TFB1/GTF2H1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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