Rabbit anti-Human TFAP2B Polyclonal Antibody | anti-TFAP2B antibody

TFAP2B, CT (TFAP2B, Transcription factor AP-2-beta, Activating enhancer-binding protein 2-beta) (Biotin)

Cat. Num. AAA6354955

• Gene Names: TFAP2B; AP-2B; AP2-B; MGC21381
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TFAP2B; Polyclonal Antibody; CT (TFAP2B; Transcription factor AP-2-beta; Activating enhancer-binding protein 2-beta) (Biotin); Activating enhancer-binding protein 2-beta; anti-TFAP2B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-TFAP2B antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TFAP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-510 amino acids from the C-terminal region of human TFAP2B.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TFAP2B Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TFAP2B antibody detected the TFAP2B protein (arrow).)

Related Product Information for anti-TFAP2B antibody

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo-or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq].

Product Categories/Family for anti-TFAP2B antibody

Antibodies; Transcription Factors

References

Li, X., et al. Genes Chromosomes Cancer 49(9):819-830(2010). Hotta, K., et al. J. Hum. Genet. (2010). In press: Ugi, S., et al. Obesity (Silver Spring) 18(7):1277-1282(2010). Nordquist, N., et al. Brain Res. 1305 SUPPL, S20-S26 (2009): Lindgren, C.M., et al. PLoS Genet. 5 (6), E1000508 (2009).

NCBI and Uniprot Product Information

• NCBI GI #: 118582289
• NCBI GeneID: 7021
• NCBI Accession #: NP_003212.2
• NCBI GenBank Nucleotide #: NM_003221.3
• UniProt Accession #: Q92481; Q5JYX6; Q9NQ63; Q9NU99; Q9UJI7; Q9Y214; Q9Y3K3
• Molecular Weight: 50,474 Da
• NCBI Official Full Name: transcription factor AP-2-beta
• NCBI Official Synonym Full Names: transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
• NCBI Official Symbol: TFAP2B
• NCBI Official Synonym Symbols: AP-2B; AP2-B; MGC21381
• NCBI Protein Information: transcription factor AP-2-beta; AP2-beta; OTTHUMP00000016595; activating enhancer binding protein 2 beta; activating enhancer-binding protein 2-beta
• UniProt Protein Name: Transcription factor AP-2-beta
• Protein Family: Transcription factor
• UniProt Gene Name: TFAP2B
• UniProt Entry Name: AP2B_HUMAN