Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7050409 at dilution of 1:100)
Rabbit anti-Human TDRD12 Polyclonal Antibody | anti-TDRD12 antibody
TDRD12 Antibody
Gene Names
TDRD12; ECAT8
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
TDRD12; Polyclonal Antibody; TDRD12 Antibody; Putative ATP-dependent RNA helicase TDRD12; ES cell-associated transcript 8 protein; Tudor domain-containing protein 12; ECAT8; anti-TDRD12 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
395
Applicable Applications for anti-TDRD12 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1: 20-1: 200
Immunogen
Recombinant Human Putative ATP-dependent RNA helicase TDRD12 protein (991-1164AA)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-248802
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Immunogen Species
Homo sapiens (Human)
Research Area
Epigenetics and Nuclear Signaling
Target Names
TDRD12
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7050409 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7050409 at dilution of 1:100)
Related Product Information for anti-TDRD12 antibody
Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
putative ATP-dependent RNA helicase TDRD12
NCBI Official Synonym Full Names
tudor domain containing 12
NCBI Official Symbol
TDRD12
NCBI Official Synonym Symbols
ECAT8
NCBI Protein Information
putative ATP-dependent RNA helicase TDRD12
UniProt Protein Name
Putative ATP-dependent RNA helicase TDRD12
Protein Family
UniProt Gene Name
TDRD12
UniProt Synonym Gene Names
ECAT8
UniProt Entry Name
TDR12_HUMAN
Uniprot Description
TDRD12: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.13
Chromosomal Location of Human Ortholog: 19q13.11
Molecular Function: ATP-dependent RNA helicase activity
Biological Process: DNA methylation during gametogenesis; fertilization; male meiosis; RNA secondary structure unwinding; RNA-mediated gene silencing; spermatogenesis
Similar Products
Product Notes
The TDRD12 tdrd12 (Catalog #AAA7050409) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TDRD12 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TDRD12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1: 20-1: 200. Researchers should empirically determine the suitability of the TDRD12 tdrd12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TDRD12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
