TAX1BP3 antibody pair

TAX1BP3 Antibody Pair

Cat. Num. AAA7041849

• Gene Names: TAX1BP3; TIP1; TIP-1
• Reactivity: Bovine, Pig
• Applications: ELISA
• Synonyms: TAX1BP3; Polyclonal Antibody Pair; TAX1BP3 Antibody Pair; Tax1-binding protein 3; Glutaminase-interacting protein 3; Tax interaction protein 1; TIP-1; Tax-interacting protein 1; TIP1; TAX1BP3 antibody pair

• Host: Capture: Rabbit; Detection: Rabbit
• Reactivity: Bovine, Pig
• Clonality: Polyclonal
• Isotype: Capture: IgG; Detection: IgG
• Form/Format: Liquid
• Concentration: The concentrations and volumes of the antibodies may vary and be lot specific. Details will be on the vial labels. (varies by lot)
• Sequence Length: 98

• Applicable Applications for TAX1BP3 antibody pair: Sandwich ELISA (EIA)
• Application Notes: We recommend using the capture antibody at a concentration of 0.5ug/ml and the detection antibody at a concentration of 0.25ug/ml.
• Immunogen Species: Human
• Conjugation: Capture: Non-conjugated; Detection: Biotin conjugated
• Recommended Standard: A-549 cell; RXF-393 cell; SW-620 cell; (Standards are recommendations only. Compatibility of the standards in the user developed application needs to be established and confirmed by the researcher.
• Storage Buffer: Capture: 50% Glycerol, 0.01M PBS, PH 7.4; Detection: 50% Glycerol, 0.01M PBS, PH 7.4
• Other Note: Immunogen information is company proprietary information. Antibodies are sold as a pair and not available separately.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze/thaw cycles. When stored properly, products should be stable for at least 5 months.

NCBI and Uniprot Product Information

• NCBI GI #: 325296954
• NCBI GeneID: 30851
• NCBI Accession #: NP_001191627.1
• NCBI GenBank Nucleotide #: NM_001204698.1
• Molecular Weight: 13,735 Da
• NCBI Official Full Name: tax1-binding protein 3 isoform 2
• NCBI Official Synonym Full Names: Tax1 binding protein 3
• NCBI Official Symbol: TAX1BP3
• NCBI Official Synonym Symbols: TIP1; TIP-1
• NCBI Protein Information: tax1-binding protein 3
• UniProt Protein Name: Tax1-binding protein 3
• Protein Family: Tax1-binding protein
• UniProt Gene Name: TAX1BP3
• UniProt Synonym Gene Names: TIP-1
• UniProt Entry Name: TX1B3_HUMAN

Uniprot Description

TAX1BP3: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.

Protein type: Cell cycle regulation; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: cytoplasm; cytosol; nucleus; plasma membrane

Molecular Function: beta-catenin binding; protein binding; protein C-terminus binding

Biological Process: negative regulation of cell proliferation; negative regulation of Wnt receptor signaling pathway; Rho protein signal transduction; Wnt receptor signaling pathway