Rabbit TAAR9 Polyclonal Antibody | anti-TAAR9 antibody

Rabbit Polyclonal to Human TAAR9

Cat. Num. AAA241416

• Gene Names: TAAR9; TA3; TAR3; TAR9; TRAR3
• Reactivity: Human; Predicted Reactivity: Hamster (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: TAAR9; Polyclonal Antibody; Rabbit Polyclonal to Human TAAR9; Anti-TAAR9 Antibody (Extracellular Domain) IHC-plus; SNORF1 receptor; TaR-3; TaR-9; TAR3; TAR9; Trace amine receptor 9; TRAR3; TA3; Trace amine receptor 3; Human TAAR9; anti-TAAR9 antibody

• Host: Rabbit
• Reactivity: Human; Predicted Reactivity: Hamster (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human TAAR9. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TAAR6 (54%).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 0.8 mg/ml (varies by lot)
• Sequence Length: 348

• Applicable Applications for anti-TAAR9 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA, IHC-P (20 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic 13 amino acid peptide from 3rd extracellular domain of human TAAR9. Percent identity with other species by BLAST analysis: Human (100%); Hamster (92%); Galago, Mouse, Rat, Bovine, Pig (85%).
• Immunogen Type: Synthetic peptide
• Immunogen: TAAR9 antibody was raised against synthetic 13 amino acid peptide from 3rd extracellular domain of human TAAR9. Percent identity with other species by BLAST analysis: Human (100%); Hamster (92%); Galago, Mouse, Rat, Bovine, Pig (85%).
• Antigen Modification: Extracellular Domain
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-TAAR9 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-TAAR9 antibody

TAAR9/TA3 is an Orphan-A GPCR because the ligand has not been identified. TAAR9/TA3 was identified by degenerate PCR because of its similarity to other trace amine receptors. The close proximity on chromosome 6 and high sequence homology to the other trace amine receptors suggest that TAAR9/TA3 is likely to bind a related or unidentified amine.

Product Categories/Family for anti-TAAR9 antibody

Family: GPCR; Subfamily: Orphan-A

NCBI and Uniprot Product Information

• NCBI GI #: 110618256
• NCBI GeneID: 134860
• NCBI Accession #: NP_778227.3
• NCBI GenBank Nucleotide #: NM_175057.3
• UniProt Accession #: Q96RI9
• Molecular Weight: 39,016 Da
• NCBI Official Full Name: trace amine-associated receptor 9
• NCBI Official Synonym Full Names: trace amine associated receptor 9 (gene/pseudogene)
• NCBI Official Symbol: TAAR9
• NCBI Official Synonym Symbols: TA3; TAR3; TAR9; TRAR3
• NCBI Protein Information: trace amine-associated receptor 9; trace amine receptor 3; trace amine receptor 9
• UniProt Protein Name: Trace amine-associated receptor 9
• Protein Family: Trace amine-associated receptor
• UniProt Gene Name: TAAR9
• UniProt Synonym Gene Names: TA3; TAR3; TRAR3; TaR-9; Trace amine receptor 9; TaR-3
• UniProt Entry Name: TAAR9_HUMAN

NCBI Description

TAAR9 is a member of a large family of rhodopsin G protein-coupled receptors (GPCRs, or GPRs). GPCRs contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Jul 2005]

Uniprot Description

TAAR9: Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; trace-amine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway