Rabbit TAAR6 Polyclonal Antibody | anti-TAAR6 antibody

Rabbit Polyclonal to Human TAAR6

Cat. Num. AAA247470

• Gene Names: TAAR6; TA4; TAR4; TAR6; TRAR4; taR-4; taR-6
• Reactivity: Chimpanzee, Human, Monkey; Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: TAAR6; Polyclonal Antibody; Rabbit Polyclonal to Human TAAR6; Anti-TAAR6 Antibody (C-Terminus) IHC-plus; TA4; TaR-4; TAR4; TAR6; TaR-6; TRAR4; Trace amine receptor 4; Trace amine receptor 6; RP11-295F4.3; Human TAAR6; anti-TAAR6 antibody

• Host: Rabbit
• Reactivity: Chimpanzee, Human, Monkey; Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human TAAR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 345

• Applicable Applications for anti-TAAR6 antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (3 - 6 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic 14 amino acid peptide from C-terminus of human TAAR6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Monkey, Marmoset (100%); Rabbit (93%); Bovine, Hamster (86%).
• Immunogen Type: Synthetic peptide
• Immunogen: TAAR6 antibody was raised against synthetic 14 amino acid peptide from C-terminus of human TAAR6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Monkey, Marmoset (100%); Rabbit (93%); Bovine, Hamster (86%).
• Antigen Modification: C-Terminus
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-TAAR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-TAAR6 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-TAAR6 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-TAAR6 antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-TAAR6 antibody

TAAR6 is classified as an Orphan-A GPCR because the ligand has not been identified. TAAR6 was identified by degenerate PCR because of its similarity to other trace amine receptors. The close proximity on chromosome 6 and high sequence homology to the other trace amine receptors suggest that TAAR6 is likely to bind a related or unidentified amine.

Product Categories/Family for anti-TAAR6 antibody

Family: GPCR; Subfamily: Orphan-A

NCBI and Uniprot Product Information

• NCBI GI #: 28173558
• NCBI GeneID: 319100
• NCBI Accession #: NP_778237.1
• NCBI GenBank Nucleotide #: NM_175067.1
• UniProt Accession #: Q96RI8; Q5VUQ4
• Molecular Weight: 38,451 Da
• NCBI Official Full Name: trace amine-associated receptor 6
• NCBI Official Synonym Full Names: trace amine associated receptor 6
• NCBI Official Symbol: TAAR6
• NCBI Official Synonym Symbols: TA4; TAR4; TAR6; TRAR4; taR-4; taR-6
• NCBI Protein Information: trace amine-associated receptor 6; trace amine receptor 4; trace amine receptor 6
• UniProt Protein Name: Trace amine-associated receptor 6
• Protein Family: Trace amine-associated receptor
• UniProt Gene Name: TAAR6
• UniProt Synonym Gene Names: TA4; TAR4; TRAR4; TaR-6; Trace amine receptor 6; TaR-4
• UniProt Entry Name: TAAR6_HUMAN

NCBI Description

This gene encodes a seven-transmembrane G-protein-coupled receptor that likely functions as a receptor for endogenous trace amines. Mutations in this gene may be associated with schizophrenia.[provided by RefSeq, Feb 2010]

Uniprot Description

TAAR6: Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; trace-amine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway