Rabbit anti-Mouse T-Box Protein 3 (TBX3) Polyclonal Antibody | anti-TBX3 antibody
Polyclonal Antibody to T-Box Protein 3 (TBX3)
MGHHHHHHSGSEF-LEAK ELWDQFHKRG TEMVITKSGR RMFPPFKVRC SGLDKKAKYI LLMDIIAADD CRYKFHNSRW MVAGKADPEM PKRMYIHPDS PATGEQWMSK VVTFHKLKLT NNISDKHGFT
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
NCBI and Uniprot Product Information
Uniprot Description
TBX3: Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS). UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 5 F|5 60.34 cM
Cellular Component: nucleus; transcription factor complex
Molecular Function: DNA binding; DNA binding transcription factor activity; sequence-specific DNA binding
Biological Process: anterior/posterior axis specification, embryo; atrioventricular bundle cell differentiation; blood vessel development; cardiac muscle cell differentiation; cell aging; cellular senescence; embryonic digit morphogenesis; embryonic forelimb morphogenesis; embryonic heart tube development; embryonic hindlimb morphogenesis; female genitalia development; follicle-stimulating hormone secretion; forelimb morphogenesis; heart looping; heart morphogenesis; in utero embryonic development; limb morphogenesis; limbic system development; luteinizing hormone secretion; male genitalia development; mammary gland development; mesoderm morphogenesis; multicellular organism development; negative regulation of apoptosis; negative regulation of epithelial cell differentiation; negative regulation of myoblast differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; organ morphogenesis; outflow tract morphogenesis; palate development; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of stem cell proliferation; positive regulation of transcription, DNA-templated; regulation of cell proliferation; regulation of transcription, DNA-templated; skeletal system development; specification of organ position; stem cell maintenance; transcription, DNA-dependent
Research Articles on TBX3
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Product Notes
The TBX3 tbx3 (Catalog #AAA2005977) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to T-Box Protein 3 (TBX3) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's T-Box Protein 3 (TBX3) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the TBX3 tbx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-LEAK ELWDQFHKRG TEMVITKSGR RMFPPFKVRC SGLDKKAKYI LLMDIIAADD CRYKFHNSRW MVAGKADPEM PKRMYIHPDS PATGEQWMSK VVTFHKLKLT NNISDKHGFT. It is sometimes possible for the material contained within the vial of "T-Box Protein 3 (TBX3), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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