Rabbit anti-Human, Mouse SYT8 Polyclonal Antibody | anti-SYT8 antibody

SYT8, ID (SYT8, Synaptotagmin-8, Synaptotagmin VIII) (APC)

Cat. Num. AAA6353062

• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SYT8; Polyclonal Antibody; ID (SYT8; Synaptotagmin-8; Synaptotagmin VIII) (APC); Synaptotagmin VIII; anti-SYT8 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-SYT8 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-100; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: SYT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human SYT8.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(SYT8 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the SYT8 antibody detected the SYT8 protein (arrow).)

Immunohistochemistry (IHC)

(SYT8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human Placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the SYT8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-SYT8 antibody

Synaptotagmins, such as SYT8, share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains. Some synaptotagmins are involved in synaptic membrane fusion, while others have a more general function in endocytosis. For further information on synaptotagmins, see MIM 185605.

Product Categories/Family for anti-SYT8 antibody

Antibodies; Syntaxin; Synaptotagmin; Synaptophysin

References

Bailey, S.D., et al. Diabetes Care (2010). In press: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Li, C., et al. Nature 375(6532):594-599(1995).

NCBI and Uniprot Product Information

• NCBI GI #: 94536846
• NCBI GeneID: 90019
• NCBI Accession #: NP_612634.3
• NCBI GenBank Nucleotide #: NM_138567.3
• UniProt Accession #: Q8NBV8; Q9NSV9; A6NFJ4
• Molecular Weight: 44,138 Da
• NCBI Official Full Name: synaptotagmin-8
• NCBI Official Synonym Full Names: synaptotagmin VIII
• NCBI Official Symbol: SYT8
• NCBI Protein Information: synaptotagmin-8; sytVIII; synaptotagmin 8
• UniProt Protein Name: Synaptotagmin-8
• Protein Family: Synaptotagmin
• UniProt Gene Name: SYT8
• UniProt Synonym Gene Names: SytVIII
• UniProt Entry Name: SYT8_HUMAN