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Western Blot (WB) (SYT8 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the SYT8 antibody detected the SYT8 protein (arrow).)

Rabbit anti-Human, Mouse SYT8 Polyclonal Antibody | anti-SYT8 antibody

SYT8, ID (SYT8, Synaptotagmin-8, Synaptotagmin VIII)

Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
SYT8; Polyclonal Antibody; ID (SYT8; Synaptotagmin-8; Synaptotagmin VIII); Anti -SYT8; anti-SYT8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-SYT8 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Immunogen
SYT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human SYT8.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SYT8 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the SYT8 antibody detected the SYT8 protein (arrow).)

Western Blot (WB) (SYT8 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the SYT8 antibody detected the SYT8 protein (arrow).)

Immunohistochemistry (IHC)

(SYT8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human Placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the SYT8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (SYT8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human Placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the SYT8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-SYT8 antibody
Synaptotagmins, such as SYT8, share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains. Some synaptotagmins are involved in synaptic membrane fusion, while others have a more general function in endocytosis. For further information on synaptotagmins, see MIM 185605.
Product Categories/Family for anti-SYT8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,138 Da
NCBI Official Full Name
synaptotagmin-8
NCBI Official Synonym Full Names
synaptotagmin VIII
NCBI Official Symbol
SYT8
NCBI Protein Information
synaptotagmin-8; sytVIII; synaptotagmin 8
UniProt Protein Name
Synaptotagmin-8
Protein Family
UniProt Gene Name
SYT8
UniProt Synonym Gene Names
SytVIII
UniProt Entry Name
SYT8_HUMAN

NCBI Description

Synaptotagmins, such as SYT8, share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains. Some synaptotagmins are involved in synaptic membrane fusion, while others have a more general function in endocytosis. For further information on synaptotagmins, see MIM 185605.[supplied by OMIM, May 2003]

Uniprot Description

SYT8: Isoform 4 may play a role in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in insulin secreted cells. Belongs to the synaptotagmin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: synaptic vesicle; plasma membrane; acrosome; integral to membrane

Molecular Function: transporter activity; calcium-dependent protein binding

Biological Process: acrosome reaction

Research Articles on SYT8

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Product Notes

The SYT8 syt8 (Catalog #AAA6008537) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYT8, ID (SYT8, Synaptotagmin-8, Synaptotagmin VIII) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SYT8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the SYT8 syt8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYT8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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