Knockout Validation
(Knockout Validation: Lane 1: Wild-type Hela cell lysate; Lane 2: STX2 knockout Hela cell lysate; Predicted MW: 33,32kd Observed MW: 33kd Primary Ab: 1ug/ml Rabbit Anti-Human STX2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Rabbit anti-Human Syntaxin 2 (STX2) Polyclonal Antibody | anti-STX2 antibody
APC/CY7-Linked Polyclonal Antibody to Syntaxin 2 (STX2)
Knockout Validation
(Knockout Validation: Lane 1: Wild-type Hela cell lysate; Lane 2: STX2 knockout Hela cell lysate; Predicted MW: 33,32kd Observed MW: 33kd Primary Ab: 1ug/ml Rabbit Anti-Human STX2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Knockout Validation
(Knockout Validation: Lane 1: Wild-type Hela cell lysate; Lane 2: STX2 knockout Hela cell lysate; Predicted MW: 33,32kd Observed MW: 33kd Primary Ab: 1ug/ml Rabbit Anti-Human STX2 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
STX2: Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 12q24.33
Cellular Component: basolateral plasma membrane; extracellular space; integral to membrane; intracellular membrane-bound organelle; lamellipodium; plasma membrane; SNARE complex; synaptic vesicle
Molecular Function: calcium-dependent protein binding; protein binding; protein dimerization activity; SNAP receptor activity; SNARE binding
Biological Process: acrosome reaction; ectoderm development; intracellular protein transport; organ morphogenesis; protein oligomerization; regulation of blood coagulation; response to hydroperoxide; signal transduction; synaptic vesicle fusion to presynaptic membrane; vesicle docking
Research Articles on STX2
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Product Notes
The STX2 stx2 (Catalog #AAA2068736) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC/CY7-Linked Polyclonal Antibody to Syntaxin 2 (STX2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Syntaxin 2 (STX2) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the STX2 stx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syntaxin 2 (STX2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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