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SDS-PAGE

Syntaxin 2 Recombinant Protein | STX2 recombinant protein

Recombinant Syntaxin 2 (STX2)

Gene Names
STX2; EPM; EPIM; STX2A; STX2B; STX2C
Applications
SDS-Page, Western Blot
Purity
> 97%
Synonyms
Syntaxin 2; Recombinant Syntaxin 2 (STX2); STX2 recombinant protein
Ordering
For Research Use Only!
Host
E.coli
Purity/Purification
> 97%
Form/Format
100mM NaHCO3, 500mM NaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.
Concentration
Original Concentration: 750ug/mL (varies by lot)
Sequence
LTA CRKNDDGDTV VVVEKDHFMD DFFHQVEEIR NSIDKITQYV EEVKKNHSII LSAPNPEGKI KEELEDLNKE IKKTANKIRA KLKAIEQSFD QDESGNRTSV DLRIRRTQHS VLSRKFVEAM AEYNEAQTLF RERSKGRIQR QLEITGRTTT DDELEEMLES GKPSIFTSDI ISDSQITRQA LNEIESRHKD IMKLETSIRE LHEMFMDMAM FVETQGEMIN NIERNVMNAT DYVEHAKEETKKAIKYQSKA RR
Sequence Length
287
Applicable Applications for STX2 recombinant protein
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB).
Organism Species
Homo sapiens (Human)
Source
Prokaryotic expression
Residues
Leu8~Arg262
Tags
N-terminal His Tag
Subcellular Location
Membrane
Traits
Freeze-dried powder
Predicted isoelectric point
5.6
Usage
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-PAGE

SDS-PAGE

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
Predicted Molecular Mass: 33.5kDa
Accurate Molecular Mass: 34kDa as determined by SDS-PAGE reducing conditions.
NCBI Official Full Name
Syntaxin 2
NCBI Official Synonym Full Names
syntaxin 2
NCBI Official Symbol
STX2
NCBI Official Synonym Symbols
EPM; EPIM; STX2A; STX2B; STX2C
NCBI Protein Information
syntaxin-2
UniProt Protein Name
Syntaxin-2
Protein Family
UniProt Gene Name
STX2
UniProt Synonym Gene Names
EPIM; STX2A; STX2B; STX2C
UniProt Entry Name
STX2_HUMAN

NCBI Description

The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

STX2: Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q24.33

Cellular Component: SNARE complex; extracellular space; synaptic vesicle; cell surface; intracellular membrane-bound organelle; lamellipodium; basolateral plasma membrane; integral to membrane; plasma membrane; endomembrane system; intercellular junction; lipid raft

Molecular Function: protein dimerization activity; SNAP receptor activity; SNARE binding; protein binding; calcium-dependent protein binding

Biological Process: synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; organ morphogenesis; response to hydroperoxide; vesicle docking; acrosome reaction; regulation of blood coagulation; ectoderm development; signal transduction; cell differentiation; protein oligomerization; regulation of cytoskeleton organization and biogenesis

Research Articles on STX2

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Product Notes

The STX2 stx2 (Catalog #AAA2029761) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Syntaxin 2 can be used in a range of immunoassay formats including, but not limited to, Positive Control; Immunogen; SDS-PAGE; Western Blot (WB). Researchers should empirically determine the suitability of the STX2 stx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LTA CRKNDDGDTV VVVEKDHFMD DFFHQVEEIR NSIDKITQYV EEVKKNHSII LSAPNPEGKI KEELEDLNKE IKKTANKIRA KLKAIEQSFD QDESGNRTSV DLRIRRTQHS VLSRKFVEAM AEYNEAQTLF RERSKGRIQR QLEITGRTTT DDELEEMLES GKPSIFTSDI ISDSQITRQA LNEIESRHKD IMKLETSIRE LHEMFMDMAM FVETQGEMIN NIERNVMNAT DYVEHAKEET KKAIKYQSKA RR. It is sometimes possible for the material contained within the vial of "Syntaxin 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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