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Western Blot (WB) (All lanes : Anti-SYNJ1 Antibody (C-term) at 1:1000-1:2000 dilutionLane 1: human brain lysateLane 2: Hela whole cell lysateLane 3: mouse brain lysateLane 4: rat brain lysateLane 5: SW480 whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 173 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit SYNJ1 Polyclonal Antibody | anti-SYNJ1 antibody

SYNJ1 Antibody (C-term)

Gene Names
SYNJ1; INPP5G; PARK20
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
SYNJ1; Polyclonal Antibody; SYNJ1 Antibody (C-term); Purified Rabbit Polyclonal Antibody (Pab); Synaptojanin-1; Synaptic inositol 1; 5-trisphosphate 5-phosphatase 1; KIAA0910; anti-SYNJ1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Ig
Specificity
This SYNJ1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1148-1182 amino acids from the C-terminal region of human SYNJ1.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
1295
Applicable Applications for anti-SYNJ1 antibody
Western Blot (WB)
Application Notes
WB ~~ 1:1000-1:2000
Antigen Source
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-SYNJ1 Antibody (C-term) at 1:1000-1:2000 dilutionLane 1: human brain lysateLane 2: Hela whole cell lysateLane 3: mouse brain lysateLane 4: rat brain lysateLane 5: SW480 whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 173 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-SYNJ1 Antibody (C-term) at 1:1000-1:2000 dilutionLane 1: human brain lysateLane 2: Hela whole cell lysateLane 3: mouse brain lysateLane 4: rat brain lysateLane 5: SW480 whole cell lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 173 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-SYNJ1 antibody
Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis.
Product Categories/Family for anti-SYNJ1 antibody
References
Haffner C.,et al.FEBS Lett. 419:175-180(1997). Nagase T.,et al.DNA Res. 5:355-364(1998). Nakajima D.,et al.DNA Res. 9:99-106(2002). Hattori M.,et al.Nature 405:311-319(2000). Cestra G.,et al.J. Biol. Chem. 274:32001-32007(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
173103
NCBI Official Full Name
synaptojanin-1 isoform c
NCBI Official Synonym Full Names
synaptojanin 1
NCBI Official Symbol
SYNJ1
NCBI Official Synonym Symbols
INPP5G; PARK20
NCBI Protein Information
synaptojanin-1
UniProt Protein Name
Synaptojanin-1
Protein Family
UniProt Gene Name
SYNJ1
UniProt Synonym Gene Names
KIAA0910
UniProt Entry Name
SYNJ1_HUMAN

NCBI Description

This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Uniprot Description

SYNJ1: Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis. Belongs to the synaptojanin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Carbohydrate Metabolism - inositol phosphate; Vesicle; EC 3.1.3.36; Phosphatase, lipid

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: membrane coat; cytosol

Molecular Function: RNA binding; phosphoinositide 5-phosphatase activity; nucleotide binding; inositol-polyphosphate 5-phosphatase activity

Biological Process: inositol phosphate metabolic process; neurotransmitter transport; phospholipid metabolic process; inositol phosphate dephosphorylation; synaptic vesicle endocytosis; synaptic vesicle transport; phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation; synaptic vesicle uncoating; phosphatidylinositol metabolic process; synaptic vesicle priming; phosphate metabolic process

Disease: Parkinson Disease 20, Early-onset

Research Articles on SYNJ1

Similar Products

Product Notes

The SYNJ1 synj1 (Catalog #AAA9216528) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYNJ1 Antibody (C-term) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SYNJ1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:1000-1:2000. Researchers should empirically determine the suitability of the SYNJ1 synj1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYNJ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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