Western Blot (WB)
(Anti-SYNJ1 Antibody (C-term)at 1:2000 dilution + K562 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 173 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human SYNJ1 Polyclonal Antibody | anti-SYNJ1 antibody
SYNJ1 Antibody (C-term)
Western Blot (WB)
(Anti-SYNJ1 Antibody (C-term)at 1:2000 dilution + K562 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 173 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(Anti-SYNJ1 Antibody (C-term)at 1:2000 dilution + K562 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 173 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Nagase T.,et al.DNA Res. 5:355-364(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Hattori M.,et al.Nature 405:311-319(2000).
Cestra G.,et al.J. Biol. Chem. 274:32001-32007(1999).
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
SYNJ1: Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis. Belongs to the synaptojanin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Phosphatase, lipid; Carbohydrate Metabolism - inositol phosphate; Motility/polarity/chemotaxis; Vesicle; EC 3.1.3.36
Chromosomal Location of Human Ortholog: 21q22.2
Cellular Component: membrane coat; cytosol
Molecular Function: RNA binding; phosphoinositide 5-phosphatase activity; nucleotide binding; inositol-polyphosphate 5-phosphatase activity
Biological Process: inositol phosphate metabolic process; neurotransmitter transport; inositol phosphate dephosphorylation; phospholipid metabolic process; synaptic vesicle endocytosis; synaptic vesicle transport; phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation; synaptic vesicle uncoating; phosphatidylinositol metabolic process; phosphate metabolic process; synaptic vesicle priming
Disease: Parkinson Disease 20, Early-onset
Research Articles on SYNJ1
Similar Products
Product Notes
The SYNJ1 synj1 (Catalog #AAA9210760) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYNJ1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SYNJ1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:2000. Researchers should empirically determine the suitability of the SYNJ1 synj1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYNJ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
