Rabbit anti-Human SWAP70 Polyclonal Antibody | anti-SWAP70 antibody

SWAP70 Antibody, FITC conjugated

Cat. Num. AAA1494308

• Gene Names: SWAP70; HSPC321; SWAP-70
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G Purified
• Synonyms: SWAP70; Polyclonal Antibody; SWAP70 Antibody; FITC conjugated; Switch-associated protein 70; SWAP-70; KIAA0640; HSPC321; anti-SWAP70 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G Purified
• Sequence Length: 527

• Applicable Applications for anti-SWAP70 antibody: ELISA (EIA)
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Conjugate: FITC
• Immunogen: Recombinant human Switch-associated protein 70 protein
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10883 / sc-10882 / sc-130887
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-SWAP70 antibody

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 663070936
• NCBI GeneID: 23075
• NCBI Accession #: NP_001284643.1
• NCBI GenBank Nucleotide #: NM_001297714.1
• UniProt Accession #: Q9UH65; O75135; Q7LCY6; Q9P061; Q9P0Z8; D3DQV1
• Molecular Weight: 68,998 Da
• NCBI Official Full Name: switch-associated protein 70 isoform 2
• NCBI Official Synonym Full Names: SWAP switching B-cell complex 70kDa subunit
• NCBI Official Symbol: SWAP70
• NCBI Official Synonym Symbols: HSPC321; SWAP-70
• NCBI Protein Information: switch-associated protein 70
• UniProt Protein Name: Switch-associated protein 70
• Protein Family: Switch-associated protein
• UniProt Gene Name: SWAP70
• UniProt Synonym Gene Names: KIAA0640; SWAP-70
• UniProt Entry Name: SWP70_HUMAN

Uniprot Description

SWAP-70: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Protein type: GEFs, Rac/Rho; GEFs

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: cytoskeleton; cytosol; lamellipodium; nucleus; plasma membrane

Molecular Function: ATP binding; calcium ion binding; DNA binding; protein binding

Biological Process: actin filament bundle formation; elevation of cytosolic calcium ion concentration; isotype switching; negative regulation of actin filament depolymerization; negative regulation of cell-cell adhesion mediated by integrin; positive regulation of actin filament bundle formation; regulation of protein localization