Rabbit anti-Human SWAP70 Polyclonal Antibody | anti-SWAP70 antibody

SWAP70 Antibody

Cat. Num. AAA9415868

• Gene Names: SWAP70; HSPC321; SWAP-70
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen Affinity Purification
• Synonyms: SWAP70; Polyclonal Antibody; SWAP70 Antibody; HSPC321; SWAP-70; anti-SWAP70 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total SWAP70 protein.
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 527

• Applicable Applications for anti-SWAP70 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:25-1:100
• Immunogen: Fusion protein of human SWAP70
• Immunogen Type: Protein
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/20.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using at dilution 1/20.)

Related Product Information for anti-SWAP70 antibody

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).

Product Categories/Family for anti-SWAP70 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 663070936
• NCBI GeneID: 23075
• NCBI Accession #: NP_001284643.1
• NCBI GenBank Nucleotide #: NM_001297714.1
• UniProt Accession #: Q9UH65; O75135; Q7LCY6; Q9P061; Q9P0Z8; D3DQV1
• Molecular Weight: 68,998 Da
• NCBI Official Full Name: switch-associated protein 70 isoform 2
• NCBI Official Synonym Full Names: SWAP switching B-cell complex 70kDa subunit
• NCBI Official Symbol: SWAP70
• NCBI Official Synonym Symbols: HSPC321; SWAP-70
• NCBI Protein Information: switch-associated protein 70
• UniProt Protein Name: Switch-associated protein 70
• Protein Family: Switch-associated protein
• UniProt Gene Name: SWAP70
• UniProt Synonym Gene Names: KIAA0640; SWAP-70
• UniProt Entry Name: SWP70_HUMAN

Uniprot Description

SWAP-70: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Protein type: GEFs; GEFs, Rac/Rho

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: cell-cell adherens junction; cytoplasm

Molecular Function: protein binding