Western Blot (WB)
(STX2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)
Rabbit anti-Human, mouse STX2 Polyclonal Antibody | anti-STX2 antibody
STX2 Antibody (Center)
Western Blot (WB)
(STX2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)
Western Blot (WB)
(STX2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)
Immunohistochemistry (IHC)
(STX2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STX2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(STX2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STX2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB)
(STX2 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)
Western Blot (WB)
(STX2 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)
syntaxin/epimorphin family of proteins. The syntaxins are a large
protein family implicated in the targeting and fusion of
intracellular transport vesicles. The product of this gene
regulates epithelial-mesenchymal interactions and epithelial cell
morphogenesis and activation. Alternatively spliced transcript
variants encoding different isoforms have been identified.
Okugawa, Y., et al. J. Invest. Dermatol. 128(8):1884-1893(2008)
Flaumenhaft, R., et al. Blood 110(5):1492-1501(2007)
Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)
Band, A.M., et al. BMC Cell Biol. 6 (1), 26 (2005) :
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
STX2: Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q24.33
Cellular Component: SNARE complex; extracellular space; synaptic vesicle; cell surface; intracellular membrane-bound organelle; lamellipodium; basolateral plasma membrane; integral to membrane; plasma membrane; endomembrane system; intercellular junction; lipid raft
Molecular Function: protein dimerization activity; SNAP receptor activity; protein binding; SNARE binding; calcium-dependent protein binding
Biological Process: synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; organ morphogenesis; response to hydroperoxide; vesicle docking; regulation of blood coagulation; acrosome reaction; ectoderm development; signal transduction; cell differentiation; protein oligomerization; regulation of cytoskeleton organization and biogenesis
Research Articles on STX2
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Product Notes
The STX2 stx2 (Catalog #AAA9208413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 123-152. The STX2 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's STX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the STX2 stx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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