Western Blot (WB)
(Western Blot analysis of BDKRB1 expression in transfected 293T cell line by BDKRB1 polyclonal antibody. Lane 1: BDKRB1 transfected lysate (38.94kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human BDKRB1 Polyclonal Antibody | anti-BDKRB1 antibody
BDKRB1 (B1 Bradykinin Receptor, BK-1 Receptor, B1R, BRADYB1)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of BDKRB1 expression in transfected 293T cell line by BDKRB1 polyclonal antibody. Lane 1: BDKRB1 transfected lysate (38.94kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of BDKRB1 expression in transfected 293T cell line by BDKRB1 polyclonal antibody. Lane 1: BDKRB1 transfected lysate (38.94kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
BKR1: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation. Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 14q32.1-q32.2
Cellular Component: neuron projection; integral to plasma membrane; endoplasmic reticulum; plasma membrane
Molecular Function: bradykinin receptor activity; protein binding; peptide binding
Biological Process: cell migration; elevation of cytosolic calcium ion concentration; negative regulation of protein amino acid phosphorylation; response to mechanical stimulus; positive regulation of leukocyte migration; protein kinase C activation; response to lipopolysaccharide; negative regulation of blood pressure; negative regulation of cell growth; positive regulation of release of sequestered calcium ion into cytosol; sensory perception of pain; inflammatory response
Research Articles on BDKRB1
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Product Notes
The BDKRB1 bdkrb1 (Catalog #AAA6009504) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BDKRB1 (B1 Bradykinin Receptor, BK-1 Receptor, B1R, BRADYB1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BDKRB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the BDKRB1 bdkrb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LASSWPPLEL QSSNQSQLFP QNATACDNAP EAWDLLHRVL PTFIISICFF GLLGNLFVLL VFLLPRRQLN VAEIYLANLA ASDLVFVLGL PFWAENIWNQ FNWPFGALLC RVINGVIKAN LFISIFLVVA ISQDRYRVLV HPMASRRQQR RRQARVTCVL IWVVGGLLSI PTFLLRSIQA VPDLNITACI LLLPHEAWHF ARIVELNILG FLLPLAAIVF FNYHILASLR TREEVSRTRC GGRKDSKTTA LILTLVVAFL VCWAPYHFFA FLEFLFQVQA VRGCFWEDFI DLGLQLANFF AFTNSSLNPV IYVFVGRLFR TKVWELYKQC TPKSLAPISS SHRKEIFQLF WRN. It is sometimes possible for the material contained within the vial of "BDKRB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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