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Western Blot (WB) (STX2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)

Rabbit anti-Human, Mouse STX2 Polyclonal Antibody | anti-STX2 antibody

STX2, ID (STX2, EPIM, STX2A, STX2B, STX2C, Syntaxin-2, Epimorphin) (APC)

Gene Names
STX2; EPM; EPIM; STX2A; STX2B; STX2C
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
STX2; Polyclonal Antibody; ID (STX2; EPIM; STX2A; STX2B; STX2C; Syntaxin-2; Epimorphin) (APC); Epimorphin; anti-STX2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-STX2 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
STX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-152 amino acids from the Central region of human STX2.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(STX2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)

Western Blot (WB) (STX2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)

Immunohistochemistry (IHC)

(STX2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STX2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (STX2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STX2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(STX2 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)

Western Blot (WB) (STX2 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the STX2 antibody detected the STX2 protein (arrow).)
Related Product Information for anti-STX2 antibody
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Product Categories/Family for anti-STX2 antibody
References
Chen, C.S., et al. J. Biol. Chem. 284(11):6877-6884(2009). Okugawa, Y., et al. J. Invest. Dermatol. 128(8):1884-1893(2008). Flaumenhaft, R., et al. Blood 110(5):1492-1501(2007). Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006). Band, A.M., et al. BMC Cell Biol. 6 (1), 26 (2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,425 Da
NCBI Official Full Name
syntaxin-2 isoform 1
NCBI Official Synonym Full Names
syntaxin 2
NCBI Official Symbol
STX2
NCBI Official Synonym Symbols
EPM; EPIM; STX2A; STX2B; STX2C
NCBI Protein Information
syntaxin-2; epimorphin
UniProt Protein Name
Syntaxin-2
Protein Family
UniProt Gene Name
STX2
UniProt Synonym Gene Names
EPIM; STX2A; STX2B; STX2C
UniProt Entry Name
STX2_HUMAN

NCBI Description

The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

STX2: Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q24.33

Cellular Component: SNARE complex; extracellular space; synaptic vesicle; cell surface; intracellular membrane-bound organelle; lamellipodium; basolateral plasma membrane; integral to membrane; plasma membrane; endomembrane system; intercellular junction; lipid raft

Molecular Function: protein dimerization activity; SNAP receptor activity; SNARE binding; protein binding; calcium-dependent protein binding

Biological Process: synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; organ morphogenesis; vesicle docking; response to hydroperoxide; acrosome reaction; regulation of blood coagulation; ectoderm development; signal transduction; cell differentiation; protein oligomerization; regulation of cytoskeleton organization and biogenesis

Research Articles on STX2

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Product Notes

The STX2 stx2 (Catalog #AAA6352336) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STX2, ID (STX2, EPIM, STX2A, STX2B, STX2C, Syntaxin-2, Epimorphin) (APC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's STX2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the STX2 stx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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