Western Blot (WB)
(STARD13 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the STARD13 antibody detected the STARD13 protein (arrow).)
Rabbit anti-Human STARD13 Polyclonal Antibody | anti-STARD13 antibody
STARD13 Antibody (Center)
Western Blot (WB)
(STARD13 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the STARD13 antibody detected the STARD13 protein (arrow).)
Western Blot (WB)
(STARD13 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the STARD13 antibody detected the STARD13 protein (arrow).)
motif domain in the N-terminus, an ATP/GTP-binding motif, a
GTPase-activating protein domain, and a STAR-related lipid transfer
domain in the C-terminus. The gene is located in a region of
chromosome 13 that has loss of heterozygosity in hepatic cancer. At
least three alternatively spliced transcript variants have been
described for this gene.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Yasuno, K., et al. Nat. Genet. 42(5):420-425(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Xiaorong, L., et al. BMC Cancer 8, 205 (2008) :
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
STARD13: GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor; Motility/polarity/chemotaxis; GAPs; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 13q13.1
Cellular Component: mitochondrial membrane; lipid particle; cytosol
Molecular Function: protein binding; lipid binding; GTPase activator activity
Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity
Research Articles on STARD13
Similar Products
Product Notes
The STARD13 stard13 (Catalog #AAA9201613) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 544-573. The STARD13 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STARD13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the STARD13 stard13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STARD13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
