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Western Blot (WB) (Western blot analysis RHG4 using Jurkat whole cell lysates)

Rabbit RHG4 Polyclonal Antibody | anti-RHG4 antibody

RHG4 Antibody

Gene Names
ARHGAP4; C1; RGC1; p115; SrGAP4; RhoGAP4
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
RHG4; Polyclonal Antibody; RHG4 Antibody; ARHGAP4; C1; p115; KIAA0131; RGC1; RhoGAP4; SrGAP4; anti-RHG4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
RHG4 Antibody detects endogenous levels of total RHG4
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
986
Applicable Applications for anti-RHG4 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human RHG4
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis RHG4 using Jurkat whole cell lysates)

Western Blot (WB) (Western blot analysis RHG4 using Jurkat whole cell lysates)
Product Categories/Family for anti-RHG4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
393
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
109,393 Da
NCBI Official Full Name
rho GTPase-activating protein 4 isoform 1
NCBI Official Synonym Full Names
Rho GTPase activating protein 4
NCBI Official Symbol
ARHGAP4
NCBI Official Synonym Symbols
C1; RGC1; p115; SrGAP4; RhoGAP4
NCBI Protein Information
rho GTPase-activating protein 4
UniProt Protein Name
Rho GTPase-activating protein 4
UniProt Gene Name
ARHGAP4
UniProt Synonym Gene Names
KIAA0131; RGC1; RHOGAP4
UniProt Entry Name
RHG04_HUMAN

NCBI Description

This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Uniprot Description

ARHGAP4: Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; cytosol

Molecular Function: GTPase activator activity; guanyl-nucleotide exchange factor activity; protein binding; Rac GTPase binding; Rho guanyl-nucleotide exchange factor activity; SH3/SH2 adaptor activity

Biological Process: cytoskeleton organization and biogenesis; negative regulation of cell migration; positive regulation of apoptosis; regulation of small GTPase mediated signal transduction; Rho protein signal transduction

Research Articles on RHG4

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Product Notes

The RHG4 arhgap4 (Catalog #AAA9419601) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RHG4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RHG4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the RHG4 arhgap4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RHG4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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