Rabbit STARD10 Polyclonal Antibody | anti-STARD10 antibody

STARD10 Polyclonal Antibody

Cat. Num. AAA3005806

• Gene Names: STARD10; PCTP2; CGI-52; NY-CO-28; SDCCAG28
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: STARD10; Polyclonal Antibody; STARD10 Polyclonal Antibody; PCTP-like protein; PCTP-L; Antigen NY-CO-28; START domain-containing protein 10; StARD10; Serologically defined colon cancer antigen 28; StAR-related lipid transfer protein 10; SDCCAG28; ORF Names: CGI-52; CGI52; anti-STARD10 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: STARD10 polyclonal antibody detects endogenous levels of STARD10 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 291

• Applicable Applications for anti-STARD10 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 105-150 of Human STARD10.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of STARD10 polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:Raw264. 7 cell lysateLane3:H9C2 cell lysate)

Related Product Information for anti-STARD10 antibody

The StARD (steroidogenic acute regulatory protein-related lipid transfer (START) domain containing) family of proteins is comprised of fifteen different members. All members contain the characteristic START domain and are believed to play key roles in the metabolism and transport of lipids. The StARD proteins are grouped into six subfamilies based on their START domain sequences. PC-TP (StARD2), StARD7, StARD10 and GPBP (StARD11) constitute one subfamily, namely the STARD2/PCTP group. StARD10, also known as PCTP2, PCTPL, NY-CO-28, CGI-52 or SDCCAG28, is widely expressed and functions in phospholipid transfer, binding to phosphatidylcholine and phosphatidylethanolamine. StARD10 can be found in sperm flagellum, potentially functioning as an enzyme involved in energy metabolism, and its expression is developmentally regulated in testis and mammary glands. StARD10 activity can be inhibited via phosphorylation by casein kinase II.

NCBI and Uniprot Product Information

• NCBI GI #: 116812600
• NCBI GeneID: 10809
• NCBI Accession #: NP_006636.2
• NCBI GenBank Nucleotide #: NP_006636.2
• UniProt Accession #: Q9Y365
• Molecular Weight: ~ 35kDa
• NCBI Official Full Name: START domain-containing protein 10
• NCBI Official Synonym Full Names: StAR related lipid transfer domain containing 10
• NCBI Official Symbol: STARD10
• NCBI Official Synonym Symbols: PCTP2; CGI-52; NY-CO-28; SDCCAG28
• NCBI Protein Information: START domain-containing protein 10
• UniProt Protein Name: PCTP-like protein
• Protein Family: PCTP-like protein
• UniProt Gene Name: STARD10
• UniProt Synonym Gene Names: SDCCAG28; PCTP-L; StARD10
• UniProt Entry Name: PCTL_HUMAN

Uniprot Description

STARD10: May play metabolic roles in sperm maturation or fertilization. Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: intercellular canaliculus; microvillus; membrane; cytosol

Molecular Function: protein binding; lipid binding

Biological Process: bile acid secretion